Immunisation Flashcards
how are communicable disease controlled?
prevent onset of disease
interrupt transmission (primary prevention)
alter course of infection/disease to prevent or limit consequences (secondary prevention)
primary prevention
Pre-exposure (in most circumstances) childhood immunisation schedule routine vaccines for older people travel vaccines occupational vaccines high risk clinical groups
secondary prevention?
Immunoglobulin - e.g. Hep B, Rabies, Varicella zoster
how do vaccines work?
Vaccines teach the immune system to recognise bacteria and viruses before the individual encounters them as potential pathogens, so allowing the body to fight against the pathogens
what are the three immunological mechanisms?
active, passive and herd immunity
what are antigens?
parts of bacteria and viruses, which are recognised by the immune system, usually proteins or polysaccharides
what does the immune system generate in response to antigens?
often by the production of antibodies
what are antibodies?
proteins which bind to antigens
they are very specific to individual antigens
what happens when an antibody-antigen complex is formed?
this alerts other immune cells (lymphocytes: B-cells and T-cells)
B cells are part of the?
humoral immune system
B cells
mature in the bone marrow
triggered to produce antibody when encounter foreign antigen