Immune System I & II

Question 1

Innate defenses

Answer 1

Barriers, phagocytes, natural killer cells, inflammatory response, and fever

Question 2

Attack cancerous cells and cells infected with viruses

Answer 2

NK cells

Question 3

Defensive molecule side of specificity

Answer 3

antibody

Question 4

Tag on target molecule

Answer 4

antigen

Question 5

A set of similar antibodies

Answer 5

Immunoglobulin class

Question 6

Two regions of an antibody molecule:

Answer 6

Variable region and the constant region

Question 7

The _____ region of an antibody molecule is different in each antibody

Answer 7

variable

Question 8

The ______ region of an antibody molecule is the same in each Ig class

Answer 8

constant

Question 9

The ______ is the part of the antigenic molecule that binds the antibody

Answer 9

epitope

Question 10

Different types of antibodies are generated by the editing of genes during the development of _____ cells

Answer 10

B cells

Question 11

Glycoproteins located at the surface of T cells

Answer 11

T cell receptors

Question 12

B lymphocytes (B cells) mature in the…..

Answer 12

Bone marrow

Question 13

T lymphocytes (T cells) mature in the……

Answer 13

thymus

Question 14

T cell receptors bind to….

Answer 14

antigens

Question 15

Adaptive defence cells derived from stem cells in the bone marrow

Answer 15

lymphocytes

Question 16

Have antibodies on their surface that serve as antigen receptors that have a specificity for a given antigen

Answer 16

B cells

Question 17

How are B cells activated?

Answer 17

By antigen binding or interaction with a helper T cell

Question 18

Clonal selection

Answer 18

Two B cell clones result from the activation of a single B cell with a single antigenic specificty

Question 19

Plasma B cells function

Answer 19

Producing antibodies that match target antigens

Question 20

Memory B cells function

Answer 20

Prolonged lifespan to remember a given antigen

Question 21

Helper T cells function

Answer 21

provide link between macrophages, humoural immunity, and cell-mediated immunity; activated helper T cells in turn activate B cells and cytotoxic T cells

Question 22

Cytotoxic T cells function

Answer 22

Poke holes in the plasma membrane of target cells; also have a line of memory T cells

Question 23

Basis for acquired immunity

Answer 23

somatic hypermutation

Question 24

Passive immunity

Answer 24

Antibodies supplied directly from the outside

Question 25

Polyclonal antibodies

Answer 25

Antibodies with different epitopic specificities and bind to different epitopes of the same antigen

Question 26

Monoclonal antibodies

Answer 26

Antibodies that all have the same epitopic specificity and bind to one epitope only

Question 27

A and B antigens on RBCs are made up of?

Answer 27

Oligosaccharide chains attached to glycolipids and glycoproteins

Question 28

Type A blood contains

Answer 28

A antigen and anti-B antibodies

Question 29

Type B blood contains

Answer 29

B antigen and anti-A antibodies

Question 30

Type AB blood contains

Answer 30

A and B antigens, and produces no anti-A or anti-B antibodies

Question 31

Type O blood contains

Answer 31

no antigens, and produces anti-A and anti-B antigens

Question 32

Consequences of transfusion of incompatable blood

Answer 32

Agglutination