Immune system Flashcards

1
Q

Antigens

A

Substances on the surface of agents that the body perceives as foreign

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2
Q

Pathogen

A

Dangerous foreign substances to the body

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3
Q

Allergies

A

Immuneoresponse to foreign agents that are not pathogens

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4
Q

Autoimmune disease

A

When the immune system mistakes part of the body as a pathogen

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5
Q

Innate immune system

A

The body’s first line of defense; a collection of nonspecific barriers- not defend against specific pathogens

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6
Q

Commensal microorginism

A

Normal bacterial flora

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7
Q

Name some antimicrobial substances in the body

A

Mucus, tears, saliva

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8
Q

What are some external (first line) aspects of the innate immune system?

A

Skin, hair, earwax, sweat, salt, enzymes, commensal microorganisms, mucus

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9
Q

What are some internal (second line) aspects of the innate immune system?

A

Inflammation, interferon, phagocytes, antimicrobials, NK lymphocytes

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10
Q

What is phagocytosis?

A

Ingestion of pathogens by WBC phagocytes

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11
Q

Macrophage

A

A phagocyte that uses digested antigens to alert T cells; also produces cytokines

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12
Q

Name 3 antigen presenting cells

A

Dendrite, B and macrophage

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13
Q

Cytokines

A

Molecules that signal the location of a pathogen to activate cytotoxic T cells (macrophage and helper T cells produce this)

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14
Q

Histamine

A

WBC that triggers capillary permeability and vasodilation so WB can leak to the infected tissues

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15
Q

Inflamation

A

Redness, swelling, heat, pain

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16
Q

Interferons

A

Proteins secreted by leukocytes that inhibit virus replication

17
Q

Adaptive immune system

A

Specific responses to particular antigens

18
Q

Lymphocytes

A

B calls and T cells

19
Q

T-cells

A

Mature in the Thymus.
Helper T- interlukins- trigger action from other cells
Cytotoxic T- attack pathogens
Memory T- Respond quickly to re-exposed pathogen, preventing symptoms

20
Q

Cell-mediated immunity

A

Adaptive immunity from T cells that attack parasites, cancer, transplanted tissues, etc.

21
Q

B-cells

A

Mature in bone marrow and make antibodies in response to antigens; turn into plasma cells that release a shload of antibodies

22
Q

Antibodies (immunoglobulins)

A

Blood proteins that fit specific antigens, marking them for destruction

23
Q

Antibody-mediated immunity (humoral immunity)

A

Immunity by antibodies created by B-cells

24
Q

Immunization

A

Active artificial immunity

25
Q

Passive immunity

A

Temporary immunity gained from an outside source i.e. placenta or breast milk

26
Q

Active immunity

A

Production of antibodies as a result in active antigens present in the body