immune system

Question 1

CCL19 and CCL21 in the lymph node

Answer 1

show molecules where to go

Question 2

Leukocyte is the broad term of

Answer 2

white blood cells

Question 3

when the tissue is damaged, immune system express…

Answer 3

chemokines

Question 4

leukocyte express “g m” and “i r” on its surface

Answer 4

glycoprotein molecules and integrin receptors

Question 5

endothelial cells will express a lot of receptors to catch the leukocytes :

Answer 5

P and E selectin

Question 6

ICAM-1 is

Answer 6

an integrin ligand on the endothelial wall interracting with the integrin receptor of leukocytes

Question 7

thanks to … the leukocyte is pulled down into the infection site

Answer 7

to the CD31 present on both the leukocyte and the endothelial cells

Question 8

what does T cells epress to interact with the epithelium tissue ?

Answer 8

a receptor of ɑ4β7 interacting with MAdCAM-1 on the epithelium tissue

Question 9

CCR7 receptor can bind 2 chemokines :

Answer 9

CCL19 and CCL21

Question 10

CCR7 receptor is expressed on the surface of :

Answer 10

B cells, T cells, dentritic cells
Once binds with CCL19 and CCL21 it guides the cell to the right zone

Question 11

G proteins are

Answer 11

signalling proteins

Question 12

G proteins and CCR7/CCL19-CCL21 controls :

Answer 12

-contractions of the cell
-movement of the cell in response to a chemical stimulus (chemokines)
-survival or apoptosis

Question 13

macrophages express a lot of

Answer 13

different receptors to recognize a lot of pathogens

Question 14

when a bacteria binds to the macrophage it initiates the

Answer 14

release of cytokine as a response

Question 15

macrophages specific receptor that recognizes yeast

Answer 15

dectin receptor