Immune system Flashcards
The 4 features of the Immune system
Specificity, diversity, distinguishing self from nonself, and Immunological immunity
The two types of responses of immune system
Humoral response and cell-mediated
response
Humoral response has _____
B CELLS(ANTIBODIES)
Cell-mediated response has_____
T CELLS
B and T cells BELONG TO THE
Lymphocytes
Bcells mature in the _____
BONE MARROW
T cells mature in the
THYMUS
Before becominng phagocytes, they are known to be
MYELOIDS
Helper T cells are helpful with
B cells and cytotoxic T cells response
Adaptive Immunity
Specific cellular response to an antigen
Antigen
A substance that elicits an immune response
Antigenic determinant
(Epitope) Small piece of antigen/small mol. structure that B AND T CELLS CAN BIND TO
AntiBODIES
Soluble proteins; PRODUCED BY B CELLS
Cytokines
Small, soluble proteins , RELEASED BY B AND T CELLS
Lymphocytes are
White blood cells
Genetic and clonal selection
Generates characteristics
Clonal selection
When a (b) cell is activated and is able to recognize a specific ANTIGEN
Mature B cells once matured will go to the
Lymphoid organs
True or false : We are born with B cells
True
Memory and plasma cells are types of
antigens
Memory cells are
LONG LIVED CELLS that responds RAPIDILY
Plasma cells are
SHORT LIVED CELLS that secretes antibodies
Antibodies have 2 regions
1) Constant 2) Variable
True or false: Both constant and variable gives
: Genetic diversity of antibodies
IGC is a type of antibody and is a
Monomer
IgM is a type of antibody and is a
Pentamer
Active immunization, as compared to passive
Extended immunological memory
HIV- AIDS is a viral disease that
Destroys the immune system
An allergy can be defined as
an exaggerated response allergen
True or false: Tuberculosis is still a world wide problem
TRUE
What cell do the most to coordinate and control the adaptive immune response
Helper T cells
The Sabin vaccine contains
Live, attenuated poliovirus
A major issue associated with the use of live attenuated viruses for vaccines is
Reversion to virulent strain that causes disease
The basis of all allergic responses lies in the production of
Histamine and mast cells
True or false : Opportunistic infections are often the proximal cause of death in individuals with immune systems that are low
True
A vaccine that employs a toxoid is based upon a
Inactivated form of a bacterial exotoxin
The two types of vaccines are
Live ( Attenuated) and Killed (Inactived)
Toxids are
Artificially made vaccines
