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ImmunoSero Continuation > Immune Response > Flashcards

Immune Response Flashcards

1
Q

Reaction of the immune system, specifically the immune cells, when the body is exposed to foreign agent

A

immune response

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2
Q

What are the factors that affect immune response?

A

Overall health status, Age, Dose/ Route of antigen administration, Genetic control of the immune response

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3
Q

True or False. Newborns’ immune system have already fully developed thus, they have strong immune response upon espodure to certain antigens.

A

False, Newborns’ immune system have not yet fully developed and is still in the process of development, thus having a weaker immune response.

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4
Q

Do geriatrics have strong or weak immune response?

A

Weak

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5
Q

The higher the dose of the antigen/the greater the antigen exposed to the immune system, the __________ (stronger or weaker) the immune response

A

stronger

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6
Q

True or False. When a person is vaccinated with a particular antigen, the dose of antigen is not considered to ensure the elicitation of immune response.

A

False. When a person is vaccinated with a particular antigen, the dose of antigen is considered to ensure the elicitation of immune response.

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7
Q

Common way of administering a vaccine is __________

A

Intramuscular/Subcutaneous

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8
Q

Best route but uncommon way of administering antigen is _________

A

Intravenous (IV)

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9
Q

It is defined as genetically controlled manner of activating and eliciting immune response

A

Major Histocompatibility Complex (MHC)

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10
Q

How many phases does primary immune response have?

A

4 (Lag, Log, Plateau, Decline)

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11
Q

The phase in the primary response wherein the antibody is not yet detectable

A

Lag Phase

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12
Q

The phase in the primary response wherein the antigen is being processed by the immune cells.

A

Lag Phase

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13
Q

The phase in the primary response wherein peak titer of the antibody is seen

A

Log Phase

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14
Q

The phase in the primary response wherein antibody titer increases logarithmically

A

Log Phase

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15
Q

The phase in the primary response wherein antibody titer stabilizes

A

Plateau/ Stationary

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16
Q

The phase in the primary response wherein there is an equilibrium/balance between antibody synthesis or production versus the antibody catabolism

A

Plateau/ Stationary

17
Q

Other name of Log Phase

A

Exponential phase

18
Q

Other name of plateau phase

A

Stationary phase

19
Q

The phase in the primary response wherein antibody catabolism is increasing

A

Decline

20
Q

The phase in the primary response wherein catabolism of antibody exceeds the production of antibody

A

Decline

21
Q

The phase in the primary response wherein antibody titer is decreasing

A

Decline

22
Q

Why does the antibody titer decreases during phase of decline?

A

Because the catabolism of antibody is greater than the production of antibody

23
Q

If the antigen is already exposed the second time, the antigenic process in the LAG phase is ________ (Longer/ Shorter) because of recognition by the memory cells.

A

Shorter

24
Q

What type of cell recognizes the reexposure of the same antigen to the body?

A

Memory cells

25
Q

If the antigen is encountered for the first time, the _________ (longer/shorter) the antigenic process is

A

Longer

26
Q

What is the first antibody to appear in the primary immune response?

A

IgM

27
Q

Elicited by a second or any subsequent exposure to the same antigen

A

Secondary immune response

28
Q

It is also known as anamnestic/ memory response

A

Secondary immune response

29
Q

Antibody titer of the Secondary Immune Response is ____________ (higher/ lower) than the Primary Response

A

Higher

30
Q

What do you call a person that is not capable of producing adequate antibodies against particular agent

A

Non-responders

31
Q

Adaptive immunity of vaccines with attenuated antigens

A

Artificial Active

ImmunoSero Continuation (2 decks)

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