Immune pathology Of Mycetoma

Question 1

What is Mycetoma?

Answer 1

Mycetoma is a chronic granulomatous inflammatory disease.

Question 2

What is the most common causative agent of eumycetoma?

Answer 2

Madurella mycetomatis is the most common causative agent of eumycetoma.

Question 3

True or False: Mycetoma is more prevalent in males than females.

Answer 3

True

Question 4

What type of immune response is typically seen in mycetoma?

Answer 4

A T-cell mediated immune response.

Question 5

What is the hallmark of mycetoma pathology?

Answer 5

Granuloma formation.

Question 6

Which cytokine is typically elevated in mycetoma?

Answer 6

Interferon-gamma (IFN-gamma).

Question 7

Fill in the blank: Mycetoma is characterized by the formation of __________.

Answer 7

Sinuses.

Question 8

What type of immune cells are found in high numbers in mycetoma lesions?

Answer 8

Macrophages and lymphocytes.

Question 9

True or False: Mycetoma lesions typically have a high fungal burden.

Answer 9

True

Question 10

What is the treatment of choice for eumycetoma?

Answer 10

Prolonged antifungal therapy.

Question 11

What is the most common site of mycetoma infection?

Answer 11

The foot.

Question 12

What is the main goal of mycetoma treatment?

Answer 12

To eradicate the infection and prevent recurrence.

Question 13

True or False: Mycetoma is a contagious disease.

Answer 13

False

Question 14

What is the role of surgery in mycetoma management?

Answer 14

To remove non-viable tissue and promote healing.

Question 15

Fill in the blank: Mycetoma is classified as a __________ infection.

Answer 15

Subcutaneous.

Question 16

What is the preferred imaging modality for evaluating mycetoma lesions?

Answer 16

Magnetic Resonance Imaging (MRI).

Question 17

True or False: Mycetoma can lead to severe deformities if left untreated.

Answer 17

True

Question 18

What is the primary method of mycetoma diagnosis?

Answer 18

Clinical examination and microbiological culture.

Question 19

What is the role of histopathology in mycetoma diagnosis?

Answer 19

To confirm the presence of granulomas and identify the causative agent.

Question 20

True or False: Mycetoma is a self-limiting disease.

Answer 20

False

Question 21

What is the main challenge in mycetoma treatment?

Answer 21

The high rate of treatment failure and recurrence.

Question 22

Fill in the blank: Mycetoma is commonly seen in __________ regions.

Answer 22

Endemic.

Question 23

What is the significance of the immune response in mycetoma?

Answer 23

It plays a crucial role in disease pathogenesis and treatment outcomes.

Question 24

True or False: Mycetoma can affect multiple body sites simultaneously.

Answer 24

True