Immune Lab Mod 1 Flashcards
Lymphocytes begin here
Red bone marrow
Lymphoid stem cells goes down 1 of 2 pathways:
NK cell or B cell
Natural killer cell does what?
Destroys cells directly
B cells do _____ destruction of the target.
Indirect
B cells released from the red bone marrow are called what?
Thymocytes
Thymocytes mature in the thymus for the prod of __ cells.
T cells
T cells that destroy the cells directly are called:
Cytotoxic t cells
Cytotoxic t cells:
Destroy cells directly
Helper t cells:
Activate b cells and recruit/activate other immune cells
Memory t cell:
Remembers specific pathogens
Plasma cells produce
Antibodies
B cells differentiate into:
Plasma cells
Complement system:
Innate
Cell-mediated
Antibody-mediated
Innate
B cells
Innate
Cell-mediated
Antibody-mediated
Antibody-mediated
Inflammation
Innate
Cell-mediated
Antibody-mediated
Innate
Skin, mucous membranes
Innate
Cell-mediated
Antibody-mediated
Innate
Interferons (IFNs)
Innate
Cell-mediated
Antibody-mediated
Innate
Cytotoxic T cells
Innate
Cell-mediated
Antibody-mediated
Cell-mediated
Plasma cells
Innate
Cell-mediated
Antibody-mediated
Antibody-mediated
Fever
Innate
Cell-mediated
Antibody-mediated
Innate
Helper t cells
Innate
Cell-mediated
Antibody-mediated
Cell-mediated/innate
NK cells
Innate
Cell-mediated
Antibody-mediated
Innate
Microphages & macrophages
Innate
Cell-mediated
Antibody-mediated
Innate
Basophils
Innate
Cell-mediated
Antibody-mediated
Innate
IgM
First antibody produced by plasma cells during an antibody-mediated response.
IgD
B cell receptor
IgG
Second antibody produced and main antibody found in plasma
IgE
Associated with allergies and parasites
IgA
Found in secretions
Antigen presenting cells
Dendrytic cells, macrophages & b cells
Spleen filters the _____
Blood
Lymph nodes filter:
Lymph
MHC proteins class 1 present on what cells?
Nucleated cells
Class 1 MHC proteins display:
Abnormal peptides of intracellular pathogens
MHC class 2 proteins display on:
Antigen-presenting cells
Class 2 MHC proteins display:
Fragments of extracellular pathogens
Opsonization:
Coat the pathogen to enhance phagocytosis
Neutralization:
Coating the pathogen; covering all components of the pathogen that can cause disease