Immune Hypersensitivities: Images (Buxton) Flashcards
EM Mast Cells
Left: IgE-coated resting mast cell
Right: antigen-activated mast cell
Stained Mast Cells
Left: IgE-coated resting mast cell
Right: antigen-activated mast cell
In the bottom left image, what is in the middle?
What are the dark purple areas?
Chronic Allergic Inflammation in Asthma
Mucous
Dead cells due to eosinophilic infiltration
What is this and which type of immune sensitivity is this?
Skin pricking test for identifying specific allergens
Type I
What is this image showing and what type of immune sensitivity does it refer to?
Skin Testing
Positive results should result in wheal & flair.
Wheal - localized edema; flair - erythema
Type I
Describe this image and identify the immune sensitivity type.
Newborn with jaundice due to hemolytic anemia from Rh incompatibility.
Type II
Describe this image and identify the immune sensitivity type.
Pemphigus vulgaris
Type II
Identify tissue samples on both the left and right.
What is happening on the right?
Left: normal tissue
Right: Pemphigus vulgaris
Big gap between basal and subepithelial layers of the epithelium
Allergic contact dermatitis - edema & mononuclear infiltrate
Type IV hypersensitivity
Allergic contact dermatitis - nickel allergy
Type IV
Allergic contact dermatitis - poison ivy
Type IV
IC deposits in joints and skin
Type III
Lung granuloma in sarcoidosis
Type IV
Normal synovial membrane
Positive TB test
Type IV
Rheumatoid arthritis
Type IV
Rheumatoid synovial membrane
Type IV
Synovial membrane of patient with advanced Rheumatoid Arthritis
Type IV
