Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

exercise and immune function > immune function > Flashcards

immune function Flashcards

1
Q

leukocytes in response to exercise

A

number in circulating blood increase, due to neutrophillia and lymphocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

for brief exercise <1 hour what does leukocytosis depend on

A

dependant on intensity, not durbstion, brief exhaustive exercise doubling leukocyte number

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

immediate leukocytosis

A

consists of neutrophils and lymphocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

delayed leukocytosis

A

some recovery in leukocyte number, second increase 2-4 hours later
sorry due to neutrophil number, lymphocyte levels below baseline
due to ingress of immature neutrophils that released from bone marrow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

innate immune system

A

naturally and immediately
first line of defence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

cells of innate immune system

A

phagocytes: neutrophils, monocytes/macrophages
natural killer cells
both responsive to exercise

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what percentage of neutrophils make up leukocytes

A

70

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

life span of neutrophils

A

5-6 days in blood, 2-3 days in tissue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

functions of neutrophils

A

chemotaxis - circulation into tissue
phagocytosis - engulf particle
degranulation and oxidative respiratory burst - kills cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

spontaneous neutrophil degranulation

A

not stimulated with LPS, exercise itself causes it

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

bacterial stimulation of neutrophil degranulation

A

stimulated with LPS not influenced by exercise

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

percentage of leukocytes made up by monocytes

A

5-15%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

lifespan of monocytes

A

1-3 days in flood

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

function of monocytes

A

phagocytosis
release of cytokines - tell immune cells what to do
Antigen Presenting Cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

dendritic cell

A

specialised antigen presenting cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what percentage of lymphocytes made up by NK cells

A

5-20%

17
Q

functions of NK cells

A

destroy virally infected, tumour cells spontaneously
release performin and activate apoptosis
most responsive immune cells to exercise, NK cell increases immediately following exercise, high number of adrenaline receptors on surface

18
Q

acute exercise NK cell and cytotoxic activity

A

increases in proportion to intensity and duration

19
Q

prolonged intense exercise NK cell and cytotoxic activity

A

decrease below baseline values for serval hours

20
Q

changed in NK cell number and function associated with what

A

hormonal changes, adrenaline, cortisol, growth hormone and beta-endorphins

21
Q

endurance training NK cell and cytotoxic activity

A

increase but may decrease with intensified training

22
Q

two main arms of acquired arm of immune system

A

cell mediated - replicate inside of cells, arms natural killer cells, t-cells
humoral - outside of cells, bacteria, activate lymphocytes

23
Q

total lymphocyte count in response to exercise

A

significant change

24
Q

causes decline in lymphocyte 2 hours post exercise

A

drops in natural killer and CD8 T cells

25
Q

what happens 4-8 hours post exercise, T cell number

A

change in CD4+ T cells
increase in eosinophils
role for T2 humoral immune response - airway inflammation

26
Q

T cell proliferation

A

cells are replictaed

27
Q

t cell proliferation exercise longer than 60 mins

A

suppressed, moderate to high intensity exercise

28
Q

Mucosal Immune System

A

largest immune network, defends respiratory, mouth, eyes, reproductive tract, intestine from infection

first line of defende

29
Q

what makes up mucosal immune system

A

mucosal associated lymphoid tissues

30
Q

most collected mucosal secretion

A

saliva, secretory immunoglobulin SIGA being majorly effector function produced

31
Q

SIGA works

A

protects mucosal surfaces, pathogen adherence, virus netrolization, excretion of immune complexes

32
Q

acute exercise and SIGA

A

acute high intensity exercise, decrease in salivary SiGA cocnetration, recovers to resting levels within one hour of exercise completion

however some studies report no change, could be down to how it’s collected and is reported

33
Q

collection for SIGA

A

stimulated, unstimulated, drool or swab

34
Q

reporting SIGA

A

concentration, secretion rate, absolute or relative

35
Q

SigA value of less than 40% of healthy value indicate

A

50% chance of being ill within 3 weeks

exercise and immune function (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions