Immune And Malignancy

Question 1

A 48-year-old woman has recently been diagnosed with node positive breast cancer and is on a protocol to receive adjuvant treatment, used in combination with surgery. Following a mastectomy, she is now scheduled for chemotherapy treatment.

The woman’s body surface area is 1.65 m2.

Pharmacy has received a prescription for:
- Epirubicin 75 mg/m2
- Fluorouracil 600 mg/m2
- Cyclophosphamide 600 mg/m2

Which one of the following is the most appropriate dose for this woman’s regimen?

• epirubicin 1.2375 mg; fluorouracil 9.90 mg; cyclophosphamide 9.9 mg
• epirubicin 123.75 mg; fluorouracil 99.0 mg; cyclophosphamide 99 mg
• epirubicin 123.75 mg; fluorouracil 990 mg; cyclophosphamide 990 mg
• epirubicin 1.2375 g; fluorouracil 9.9 g; cyclophosphamide 9.9g
• epirubicin 12.375 g; fluorouracil 99g; cyclophosphamide 99 g

Answer 1

Epirubicin 123.75mg; Fluorouracil 990mg; Cyclophosphamide 990mg