Immune And Lymphatic System

Question 1

What is the response of innate immunity? And why is that?

Answer 1

Inflammation because it lacks immune specificity and memory

Question 2

What are the first responders of innate immunity?

Answer 2

Neutrophils

Question 3

Acquired immunity develops in response to antigens? What does this signify?

Answer 3

Specificity and memory

Question 4

Passive immunity is a temporary immunity due to donated what?

Answer 4

Antibodies

Question 5

Active immunity is a long-lasting/permanent immunity due to self exposure to antigen resulting in?

Answer 5

Memory T cells and B cells specific for antigen

Question 6

What are the primary lymphoid organs

Answer 6

Thymus and bone marrow

Question 7

What are the secondary lymphoid organs?

Answer 7

Lymph nodes, spleen, tonsils

Question 8

Are spherical, tightly packed accumulations of virgin B cells and dendritic reticular cells that have not been exposed to antigens, describes what?

Answer 8

Primary follicles

Question 9

Are derived from primary follicles that have been exposed to non-self antigens, and not present at birth describes?

Answer 9

Secondary follicles

Question 10

Lymph follicles are sites of B cell localization and proliferation. T/F?

Answer 10

True

Question 11

Subcutaneous-associated lymphoid tissue is found in the __ layer of the dermis

Answer 11

Papillary

Question 12

Aggregated lymphoid tissue is beneath and in contact with the epithelium which includes…

Answer 12

Various tonsils and Peyer’s patches in the ileum

Question 13

IgA are found where?

Answer 13

Saliva, milk, GU and respiratory tracts

Question 14

IgD are found where?

Answer 14

On surfaces of B cells traveling to lymphoid organs

Question 15

IgG responsible for?

Answer 15

Responsible for most antibody activity

Question 16

IgE associated with what type of responses?

Answer 16

Allergic responses

Question 17

IgM is the first antibody class expressed by developing __ cells?

Answer 17

B cells

Question 18

What is the main function of major histocompatibility complex? (MHC)

Answer 18

Present antigenic peptides to T cells

Question 19

CD8 sis a member of what superfamily?

Answer 19

Ig superfamily

Question 20

Cd4+ T cells are helper cells that assist in __ cell differentiation

Answer 20

B cell

Question 21

CD8+ T cells release…

Answer 21

Perforins and Fas ligand

Question 22

CD16+ T cells aka

Answer 22

Natural killer T cells

Question 23

Dense collagen fibers, some elastic fibers, and smooth fibers describe what part of a lymph node?

Answer 23

Capsule

Question 24

What is the entry and exit point for vessels in a lymph node?

Answer 24

Hilus

Question 25

The outer cortex of a lymph node contains what?

Answer 25

Lymph follicles

Question 26

The cortex follicles of a lymph contain: B cells, follicular dendritic cells, and migrating dendritic cells. T/F?

Answer 26

True

Question 27

The deep (inner) cortex of a lymph node contain HEVs. T/F?

Answer 27

True

Question 28

The medulla of a lymph node is the site of lymphocyte reentry into lymph stream? T/F?

Answer 28

True

Question 29

Medulla or lymph node is an irregular arrangement of loose/tight medullary sinuses and dense/thin medullary cords

Answer 29

Loose medullary sinuses and dense medullary cords

Question 30

The cortex lobule of the thymus stains dark or light?

Answer 30

Dark

Question 31

The medulla of thymus lobule stains dark or light?

Answer 31

Light

Question 32

Double negative T cells enter cortex from __ and proliferate in __ area

Answer 32

From blood vessels, subcapsular area

Question 33

Double positive T cells move to __ cortex

Answer 33

Outer

Question 34

Single positive T cells move to __ cortex

Answer 34

Inner

Question 35

Spleen filters...

Answer 35

Blood

Question 36

Spleen converts hemoglobin to

Answer 36

Bilirubin

Question 37

Spleen produces what 2 types of cells?

Answer 37

Lymphocytes and plasma cells

Question 38

Spleen: T cells are found in the areas surrounding the central artery near the center of the white pulp. Forms the ___ sheath?

Answer 38

Pariarterial lymphatic sheath (PALS)

Question 39

Spleen: Macrophages destroy worn-out or defective RBCs/WBCs?

Answer 39

RBCs

Question 40

Spleen: Venous sinusoids are the storage site for healthy __ cells?

Answer 40

RBCs

Question 41

Splenic artery enters __

Answer 41

Hilus

Question 42

Spleen: After capillaries form, supplying white pulp, central arteries lose their white pulp investment and enter red pulp to form a ___

Answer 42

Penicillus

Question 43

Spleen: Venous sinuses are line with ___ cells?

Answer 43

Reticuloendothelial cells

Question 44

Consists of cells that typically pack areas of the lymphoid organ (mostly lymphocytes) describes...

Answer 44

Parenchyma

Question 45

Consists mostly of reticular fibers and cells, including undifferentiated cells and fixed and free macrophages describes...

Answer 45

Stroma

Question 46

Structure of a secondary lymph follicle contains a corona (cortex) and a germinal center. How do they stain?

Answer 46

Corona stain dark in its peripheral region and germinal center stains lighter

Question 47

IgM produces what kind of lymphocytes?

Answer 47

B lymphocytes

Question 48

MHC II is expressed where?

Answer 48

On the surface of B cels and antigen-presenting cells

Question 49

MHC I helps in autoimmunity how?

Answer 49

Identifies self from foreign

Question 50

CD4+ cells aka

Answer 50

Helper Cells

Question 51

CD4+ recognize antigens bound to what MHC class molecules?

Answer 51

MHC II

Question 52

CD8+ aka

Answer 52

Cytolytic T cells

Question 53

CD8+ cells recognize antigens bound to what MHC class molecules?

Answer 53

MHC I

Question 54

What is the site of lymphocyte reentry into lymph stream?

Answer 54

Medulla

Question 55

Double negative T cells proliferate where?

Answer 55

Subcapsular area

Question 56

Double positive T cells express what king of receptors?

Answer 56

BOTH CD4 and CD8 coreceptors and TCR receptors

Question 57

What kind of receptors do single positive T cells express?

Answer 57

TCR receptors and EITHER CD4 or CD8 coreceptors

Question 58

Billroth cords form red or white pulp parenchyma?

Answer 58

Red pulp