Immune Flashcards
1
Q
When would a child with Immune Thrombocytopenia require treatment?
A
Platelet count <10 x10^9/L
No active bleeding
2
Q
What advice would you give a patient and their parents if they have a non-severe ITP?
A
80% of patients do have full resolution of the ITP with or without treatment. Advice to avoid any trauma is crucial and safety net.
3
Q
What is Immune Thrombocytopenia (ITP)?
A
Immune thrombocytopenia is when antibodies are created against the glycoprotein IIb/IIIa or Ib-V-IX complex. This leads to an immune mediated reduction in platelet count and is an example of a type 2 hypersensitivity reaction.
4
Q
What can rhesus incompatibility syndrome cause?
A
Haemolysis
Severe hyperbilirubinaemia (leading to jaundice)
Anaemia
