IMMS Flashcards
Mitochondria structure
double envelope membrane, folded into cristae (increase SA)
Which processes take place in mitochondria (and specifically where)
- matrix, TCA cycle, link reaction and beta oxidation
- outer mem, lipid synthesis and FA metabolism
- inner mem, resp chain and ATP production
- inner mem space, ADP->ATP phosphorylation
Types of endoplasmic reticulum and their function
- rough ER, packages proteins
- smooth ER, detox of hydrophobic molecules and mem lipid synthesis
- sarcoplasmic R, stores and releases Ca2+
Golgi apparatus function
modification and packaging of proteins
Vesicle function
transport of proteins and enzymes
Peroxisomes function
- consumes molecular oxygen
- removes hydrogen from lipids, alcohol and toxic substances
- produces H202 (can also destroy)
- FA breakdown
Components of cytoskeleton
1) actin filaments (G & F actin)
2) intermediate filaments (nuclear laminin, keratin)
3) microtubules (tubulin)
Structure of cell membrane
- phospholipid bilayer
- cholesterol
- proteins
- sphingolipids
- glycolipids
Function of cell membrane
1) barrier
2) detect chemical messengers arriving at cell surface
3) link adjacent cells
4) anchor cells to ECM
5) endo/exocytosis
6) allows AP to occur
Role of proteins in cell membrane
1) receptors to receive messages
2) protein channels to control cell content
3) maintains structural integrity
4) bind cell to ECM and anchor cells
5) AT pumps
What makes up cilia?
Tubulin and dyenin
Types of membrane proteins
1) G couples protein receptors (transduction pathways)
2) voltage gated channels (open at certain MP)
3) ligand gated channels (open when something binds to them)
4) mechanically gated channels (open when stretched)
Types of cell junction
1) tight, stop certain substances passing through
2) gap, allow passage of small molecules
3) desmosomes, allow degree of stretch (mainly structural not functional)
Types of movement across a cell membrane
1) diffusion
2) facilitated diffusion
3) primary AT
4) secondary AT (coupled)
5) exocytosis
6) endocytosis (basic, pinocytosis, receptor mediated)
glucose + glucose =
sucrose