immnuology

Question 1

Good pasture syndrome

Answer 1

against bm of kidneys and lnugs

type 2

Question 2

graves disease

Answer 2

against TSH receptor

type 2

Question 3

myasthenia gravis

Answer 3

type 2

nicotinic Ach receptor

Question 4

ANA, anti-dsDNA

Answer 4

SLE

Question 5

Anti histone

Answer 5

drug induced lupus

Question 6

anti Rnp

Answer 6

mixed connective tissue disease

Question 7

Anti Centromere

Answer 7

CREST syndrome

Question 8

CREST?

Answer 8

Calcinosis
raynaud's phenomenan 
esophageal dysmotility
sclerodactyly
telangectasia

Question 9

Anti Scl

Answer 9

Diffuse scleroderma

Question 10

Anti SS A

Answer 10

Sjögren’s syndrome

Question 11

arthus reaction

Answer 11

type 3

Question 12

serum sickness

like horse serum or foreign body

Answer 12

type 3

Question 13

PSGn

Answer 13

type 3

Question 14

IgA nephropathy

Answer 14

Type 3

Question 15

contact dermatitis

Answer 15

type 4

Question 16

guillan barre

Answer 16

type 4

campylobacter jejuni
ascending neuromascular degeneration

Question 17

type 1 dm

Answer 17

type 4

Question 18

ibs

Answer 18

type 4

Question 19

multiple sclerosis

Answer 19

anti MBP ab

type 4

Question 20

chronic transplant rejection

Answer 20

type 4

Question 21

hashimotos thyroiditis

Answer 21

type 4
anti TPO
presents with hypothyroidism

Question 22

drugs that induces lupus

Answer 22

Hydralazine
isoniazid
procainamide
penicillamine

Question 23

triad of Sjögren’s

Answer 23

dry eyes keratoconjnutivitis
dry mouth xerostomia
arthritis

Question 24

drugs for Sjögren’s

Answer 24

corticosteroids
artificial tears
pilocarpine

Question 25

hyper acute rejection

Answer 25

type 2

Question 26

acute cellular rejection

Answer 26

type 4

Question 27

acute humoral rejection

Answer 27

type 2

Question 28

chronic rejection

Answer 28

type 4

Question 29

very low levels of all immunoglobulins

virtual absence of Bcells due to tyrosine kinase mutation
recurrent pyogenic bacterial infections

Answer 29

male infant abt 6months

xlinked hypogammaglobilinemia
brutons agammaglobulinemia

Question 30

failure of isotoe switching

Answer 30

selective IgA deficiency

Question 31

most common form of severe ab deficiency

defect in b cell maturation to plasma cells

Answer 31

common variable immunodeficiency

Question 32

profound t cell deficit

catch22

Answer 32

digeorge

Question 33

soecific t cell def against Candida albicans

Answer 33

chronic mucocutaneous candidiasis

Question 34

mutation in gene encoding common gamma chain/IL 2 receptor gamma
infection as early as 3 months

Answer 34

Severe combined immunodeficiency

enclose plastic bubble

Question 35

wasp gene

x linked

Answer 35

wiskott aldrich

Question 36

triad of wasp

Answer 36

thrombocytopenia
infection
eczema

Question 37

lack of oxidase activity

failure of oxidative burst i.e. can contain the agent but cannot burst recurrent catalase positive infection

Answer 37

chronic granulomatois disease

pigsain!

Question 38

failure of phagolysosomal fusion

Answer 38

chediak higaahi syndrome

Question 39

autosomal recessive
defective adhesion (LFA-1) proteins
LAZY!

Answer 39

leukocyte adhesion deficiency

severe pyogenic infection in infancy
delayed separation of umbilical cord

Question 40

ARF

Answer 40

Type 2 M proteins