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Patho/IM > immnuology > Flashcards

immnuology Flashcards

1
Q

Good pasture syndrome

A

against bm of kidneys and lnugs

type 2

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2
Q

graves disease

A

against TSH receptor

type 2

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3
Q

myasthenia gravis

A

type 2

nicotinic Ach receptor

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4
Q

ANA, anti-dsDNA

A

SLE

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5
Q

Anti histone

A

drug induced lupus

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6
Q

anti Rnp

A

mixed connective tissue disease

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7
Q

Anti Centromere

A

CREST syndrome

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8
Q

CREST?

A 
Calcinosis
raynaud's phenomenan 
esophageal dysmotility
sclerodactyly
telangectasia
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9
Q

Anti Scl

A

Diffuse scleroderma

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10
Q

Anti SS A

A

Sjögren’s syndrome

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11
Q

arthus reaction

A

type 3

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12
Q

serum sickness

like horse serum or foreign body

A

type 3

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13
Q

PSGn

A

type 3

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14
Q

IgA nephropathy

A

Type 3

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15
Q

contact dermatitis

A

type 4

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16
Q

guillan barre

A

type 4

campylobacter jejuni
ascending neuromascular degeneration

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17
Q

type 1 dm

A

type 4

18
Q

ibs

A

type 4

19
Q

multiple sclerosis

A

anti MBP ab

type 4

20
Q

chronic transplant rejection

A

type 4

21
Q

hashimotos thyroiditis

A

type 4
anti TPO
presents with hypothyroidism

22
Q

drugs that induces lupus

A

Hydralazine
isoniazid
procainamide
penicillamine

23
Q

triad of Sjögren’s

A

dry eyes keratoconjnutivitis
dry mouth xerostomia
arthritis

24
Q

drugs for Sjögren’s

A

corticosteroids
artificial tears
pilocarpine

25
Q

hyper acute rejection

A

type 2

26
Q

acute cellular rejection

A

type 4

27
Q

acute humoral rejection

A

type 2

28
Q

chronic rejection

A

type 4

29
Q

very low levels of all immunoglobulins

virtual absence of Bcells due to tyrosine kinase mutation
recurrent pyogenic bacterial infections

A

male infant abt 6months

xlinked hypogammaglobilinemia
brutons agammaglobulinemia

30
Q

failure of isotoe switching

A

selective IgA deficiency

31
Q

most common form of severe ab deficiency

defect in b cell maturation to plasma cells

A

common variable immunodeficiency

32
Q

profound t cell deficit

catch22

A

digeorge

33
Q

soecific t cell def against Candida albicans

A

chronic mucocutaneous candidiasis

34
Q

mutation in gene encoding common gamma chain/IL 2 receptor gamma
infection as early as 3 months

A

Severe combined immunodeficiency

enclose plastic bubble

35
Q

wasp gene

x linked

A

wiskott aldrich

36
Q

triad of wasp

A

thrombocytopenia
infection
eczema

37
Q

lack of oxidase activity

failure of oxidative burst i.e. can contain the agent but cannot burst recurrent catalase positive infection

A

chronic granulomatois disease

pigsain!

38
Q

failure of phagolysosomal fusion

A

chediak higaahi syndrome

39
Q 
autosomal recessive
defective adhesion (LFA-1) proteins
LAZY!
A

leukocyte adhesion deficiency

severe pyogenic infection in infancy
delayed separation of umbilical cord

40
Q

ARF

A

Type 2 M proteins

Patho/IM (5 decks)

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