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Ellen Haematology > Imme Therapies > Flashcards

Imme Therapies Flashcards

1
Q

What class is dabigatran and what can be used to reverse it?

A

Direct thrombin (2a) inhibitors
Idracizumab

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2
Q

What treatment is used for T-ALL?

A

Inotuzumab

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3
Q

What treatment is used for B-ALL?

A

Blinatumumab

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4
Q

What treatment is used in the case of ALL 9;22 translocation?

A

Imatinib

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5
Q

What treatment can be used for CML in the presence of FLT3 mutations?

A

Midostaurin

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6
Q

What treatment can be used in the presence of CD33?

A

Gemtuzumab
Myeloid CD

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7
Q

What treatment can be used for CML in the presence of IDH mutations?

A

Enasidenib

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8
Q

What agent is anti CD-20 and what condition is this useful in?

A

Rituximab
CLL (CD20 on B cells)

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9
Q

What agent is a BTK inhibitor and what condition is this useful in?

A

Irutinib
CLL

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10
Q

What agent is a BCL2 inhibitor and what condition is this useful in?

A

Venetoclax
CLL

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11
Q

What combination chemo is used in treating Hodgkins Lymphoma?

A

Adriamycin
Bleomycin
Vinblastine
Dacarbazine

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12
Q

What therapy can be used to treat any B cell lymphoma?

A

Rituximab
CD20 B cell

B cell lymphoma more common than T cell

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13
Q

What therapy can be used to treat any T cell lymphoma?

A

Alemtuzumab

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14
Q

How do you manage multiple myeloma?

A

Supportive for CRAB symptoms eg bisphosphonates
Bortezomib

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15
Q

How do you treat myelodysplastic syndromes?

A

Supportive
Immunosuppressive- lenalidomide
Chemo for AML

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16
Q

What immune modulation is used in MS?

A

Corticosteroids
Interferon B

17
Q

What immune modulation is used in RhA?

A

Steroids
DMARDs

18
Q

What immune modulation is used in Crohns?

A

Mesalazine
TNF-a antagonist Infliximab

19
Q

What treatment can be used for advanced melanoma?

A

Ipililumab
CTLA4 antibody- T cell specific

20
Q

What is prednisolone MOA?

A

Inhibits Phospholipase 2
No prostaglandins

Ellen Haematology (2 decks)

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