IMM 21 and 22: Labs & Diagnostic Tests Flashcards

1
Q

What must pharmacists have to order lab tests? (5)

A
  • professional relationship with patient
  • competence to order the correct test and interpret results
  • patient consent
  • no conflict of interest
  • access to patient information to determine: if a lab test is required, which lab test to order, interpretation of result in context of patient, actions to be taken in response to results
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2
Q

What are additional requirements for pharmacists to order lab tests?

A

test ordering must be to provide services within pharmacist scope of practice

  • identifying, assessing and resolving drug therapy problems
  • monitoring drug therapy
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3
Q

What are the steps to determine if you should order a lab test?

A
  1. complete clinical assessment of subjective and objective findings
  • if lab results will not change your decision-making, do NOT order it
  • ie. patient has all the symptoms of uncomplicated cystitis, for which you can
    prescribe
  1. consider what you would do with a lab result that is high, low, or normal
  • if you wouldn’t do anything different, do NOT order it
  • ie. rivaroxaban is an anticoagulant (blood thinner) known to increase INR – INR is not used to adjust dose or change therapy for
    rivaroxaban

3a. review available blood work to determine when the test was last ordered

  • what is the likelihood that the results have changed since it was last measured
  • has the patient’s medications or adherence to their medications changed
  • has the patient’s medical conditions changed in a way that might change their lab results
  • has enough time passed since the change that you would expect to see a difference in their labs
  • how frequently do clinical practice guidelines recommend that this test is performed

3b. review available blood work to determine what other tests have been done

  • has another test been done that provides the same/similar information
  1. determine if the patient already has a requisition from another healthcare provider to order the required laboratory tests
  • if so, do NOT duplicate ordering of the laboratory test
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4
Q

What is the problem with unnecessary tests?

A
  • costs to patient and health system
  • inconvenience to patient
  • may result in inappropriate treatment decisions – ie. f a test is performed too early, a medication may be unnecessarily increased or decreased
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5
Q

Which tests can pharmacists order?

A
  • hematology profile (CBC)
  • anemia markers (B12, ferritin, iron, transferrin)
  • electrolytes: sodium, potassium, chloride, calcium, magnesium, phosphate
  • renal tests: creatinine, GFR, urinalysis, albumin/creatinine ratio, 24H CrCl
  • liver tests: INR, albumin, bilirubin, alk phos, ALT, AST, GGT, LDH, total protein
  • endocrine tests: A1c, fasting BG, random BG, TSH
  • cardiovascular: lipid profile, CK
  • therapeutic drug levels
  • drug screening
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6
Q

What are the responsibilities of pharmacists upon ordering tests?

A
  • obtain informed and voluntary consent from the patient or caregiver
  • discuss distribution of the results to other healthcare professionals, such as family physician
  • inform the patient is a laboratory test is not covered by the Medical Services Plan
  • inform the patient of any testing requirements (fasting, sample collection, etc)
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7
Q

Do pharmacists have to get permission from the patient’s physician to order lab tests?

A

no

  • pharmacist may, in collaboration with the patient, decide to have the results sent to other members of the patients care team
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8
Q

What do pharmacists have to do upon receiving lab test results?

A

pharmacist’s responsibility to ensure that lab results received are interpreted and acted upon in a timely fashion

  • must communicate the results and plan to the patient in a timely manner
  • cannot rely on patient’s primary care provider to respond to laboratory results, even if the labs were copied to them
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9
Q

What might a pharmacist do after receiving and interpreting lab test results?

A
  • make necessary modifications to patient’s care plan
  • discussing results with patient’s other healthcare providers
  • refer the patient to another healthcare provider for assessment
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10
Q

How quickly do pharmacists need to respond to lab test results?

A

depends on the results received and the degree of abnormality

  • normal results: must be communicated with the patient, but can be at a time that is convenient for patient and pharmacist
  • abnormal results: depends on how abnormal the results are
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11
Q

What are critical values?

A

values markedly outside of reference ranges that indicate the potential for significant risk of life-threatening events

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12
Q

When do critical values need to be assessed?

A

immediately (24hrs/day, 7 days/week)

  • Lab Operator will call the ordering pharmacist, or predetermined alternate, if a critical result is identified
  • pharmacist is responsible for immediately assessing and acting upon the result
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13
Q

What do pharmacists have to do if a critical lab result is unexpected?

A

must refer the patient to the emergency department or other source of medical care

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14
Q

What are non-critical abnormal values?

A

values outside the reference range, but less likely to cause significant risk of life-threatening

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15
Q

What do pharmacists have to do with non-critical abnormal values?

A
  • communicate the results to the patients
  • determine a plan of care – may include alteration of drug therapy, or referral to another medical professional for assessment and management
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16
Q

What are the steps to interpret lab test results?

A
  1. assess results for degree of abnormality and determine if it is a critical value
  2. assess the degree of change from previous measurements, including:
  • has the patient’s medications or adherence to their medications changed
  • has the patient’s medical conditions changed in a way that might change their lab results
  • has enough time passed since the change that you would expect to see a difference in their labs
  1. make a plan for adjustment of pharmacotherapeutic regimen, if required
  2. communicate plan with patient +/- other healthcare providers
17
Q

What are the factors to consider when interpreting lab test results?

A

factors that can lead to imprecision of results

  • biologic variation
  • analytic variation
  • laboratory or collection error

knowing the possibility in variation of tests results can help to determine if the change seen is a reflection of a true biologic difference

18
Q

When might pharmacists provide interpretation of tests ordered by another healthcare professional?

A

results are pertinent to the pharmacist services provided

AND

pharmacist understands the context in which the test was ordered

19
Q

What do pharmacists have to document in the clinical record upon ordering and interpreting lab test results?

A
  • client information
  • informed consent
  • test ordered and rationale for ordering
  • date ordered
  • results received
  • actions taken in response to received results
  • healthcare professional to whom the results were forwarded (if at all)
20
Q

What are the limits upon pharmacist lab test ordering?

A
  • pharmacists must only order labs that are within the pharmacist’s knowledge and competence to order and interpret
  • pharmacists must not order lab tests for themselves or family members (EXCEPT in emergency situations and another practitioner is not available)
21
Q

Are pharmacists required to order lab tests?

A

no – however, they must always act in the patient’s best interest

  • if they chose not to order laboratory tests when the test would benefit the patient, they must be able to defend that decision and refer the patient to a practitioner willing and able to order the test
22
Q

How do you calculate creatinine clearance?

A

[(140 - age) x weight x 1.23] / SCr

23
Q

What is hypothyroidism?

A
  • increased TSH
  • decreased T4
24
Q

What is hyperthyroidism?

A
  • decreased TSH
  • increased T4