imersive simulations- error at handover

Question 1

treatment of nsaid toxicity

Answer 1

Haematology and biochemistry-
Often normal, especially in acute, asymptomatic cases.
Most useful for monitoring and symptomatic cases.

Intravenous fluid therapy-
Replace fluid loses e.g. from vomiting
Maintain renal perfusion and diuresis

Toxicology:
Aspirin: Stimulates the respiratory centre -> hyperventilation and respiratory alkalosis, -> metabolic acidosis over time.
Paracetamol: Toxic metabolite which induces cellular necrosis, methaemoglobin, and Heinz body formation.
Ibuprofen: Non -selective COX inhibitor; toxicity due to COX-1 inhibition

Meloxicam is a non-steroidal anti-inflammatory drug (NSAID) of the oxicam class which acts by inhibition of prostaglandin synthesis, thereby exerting anti-inflammatory, analgesic, anti-exudative and antipyretic effects.

clinical effects-
Depression, vomiting, anorexia, hyperthermia, tachypnoea, haematemesis, melaena, abdominal tenderness and anorexia.

treatment-
Fluid therapy
Oxygen therapy (if required)
Antiemetics (if required)
Gastroprotectants e.g. sucralfate, ranitidine or famotidine, omeprazole
Monitor renal and hepatic enzymes, electrolytes, and acid-base changes.