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MIMS > Imaging techniques > Flashcards

Imaging techniques Flashcards

1
Q

MRI Key Imaging - fMRI

A

fMRI:

  • BOLD (Blood Oxygen Dependent Levels):
  • deoxyHb paramagnetic
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2
Q

PET Key Imaging

A

Fluorine 18

  • FDG (Flurodeoxyglucose) –> Glucose Usage
  • Flurothymidine and Thymidine Kinase: Upreg in proliferating cells for DNA synthesis
  • Iodine 125: used with SPECT imaging for apoptosis Signals
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3
Q

MRI Key Imaging: dDNP

A

dDNP: Dissolution Dynamic Nuclear Polarisation

- 13C pyruvate tracking, LDH levels

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4
Q

MRI Key Imaging: Angiognesis and Diffusion Weight MRI

A

Angio-genesis: Gadolinium

Diffusion Weighting MRI: Water and Apparent diffusion Coefficient

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5
Q

SPECT imaging: Apoptosis in tumours

A

Annexin V binds to phosphatidylserine
Binds to Technetium-99m also
Combined with positron emitter such as Iodine-125

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6
Q

Fluorescent Imaging - Guiding Surgery

A

Ovarian Tumours

Folate A receptor: Folate Conjugated to Fluorescein isothiocynate –> (internalised receptor and ligand)

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MIMS (5 decks)

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