ILA 4 - THROMBOSIS AND COAGULATION

Question 1

Describe the Normal Coagulation Cascade

Question 2

Explain the difference in presentation (signs and symptoms) between an arterial thrombosis and a venous thrombosis

Question 3

Describe Virchow’s triad and explain the pathophysiology of thrombus development

Question 4

What risk factors does Ali have and how do these relate to Virchow’s triad?

Question 5

What blood tests would you do to help confirm the diagnosis of a DVT?
Why does the blood level of this ‘substance’ increase with the presence of a DVT?

Question 6

Heparin and warfarin are used in the treatment of DVT. In relation to the coagulation cascade, explain the action of each

Question 7

Ali leaves hospital a few days later. What potentially fatal complication of a DVT should they be made aware of and what signs and symptoms should they look out for?

Answer 7

Complication: Pulmonary embolus

Question 8

What advice would you give to students who need to take long haul flights in order to reduce their risk of developing a DVT?

Answer 8

If travelling for more than 3hrs b plane, train, or car:
- wear loose, comfortable clothes
- do calf exercises at least every 30mins
- walk around whenever you can
- drink plenty of water
- do not drink alcohol or take sleeping pills
- compression stockings