II. (Gene Interactions - Pleiotropism) Flashcards
____ is the joint role or influence of multiple genes on the same character or phenotype.
Gene Interaction
In ____, the independent (non-homologous) genes located on the same or on different chromosomes interact with one another for the expression of a single phenotypic trait of an organism.
Interallelic Genetic Interactions
In ____, two pairs of genes determine the same phenotype but are assorted independently and produce new phenotypes by mutual genetic interaction.
Non-epistatic Interallelic Genetic Interaction
___ occurs when one gene masks or modifies the effect of another gene pair and alters the phenotype.
Epistasis
___ occurs when the recessive allele of one gene masks the effects (phenotypic expression) of either allele of the second gene.
Recessive Epistasis
____ is caused by the dominant allele of one gene, masking the action of either alleles of the other gene.
Dominant Recessive
___ occurs when a dominant allele of one gene completely suppresses the phenotypic expression of alleles of another gene.
Dominant Suppression
____ occurs when both gene loci have homozygous recessive alleles and both of them produce identical phenotypes thus generating the F2 9:7 phenotypic ratio.
Complementary Epistasis or Duplicate Recessive Epistasis
___ occurs when the dominant alleles of both gene loci produce the same phenotype without cumulative effect, modifying the F2 phenotypic ratio into 15:1.
Duplicate Dominant Epistasis
____ occurs when two genes are involved in the expression of the shape; each gene is completely dominant; interaction between the two loci produces a new phenotype.
Dominant Gene Interaction
____ refers to the combined effects of genetic alleles at two or more gene loci that are equal to the sum of their individual effects.
Duplicate Genes with Additive/Cumulative Effect
___ is the phenomenon of multiple effects (multiple phenotypic expressions) of a single gene; one gene influences two or more seemingly unrelated phenotypic traits.
Pleiotropism
What are some examples of pleiotropy?
- Phenylketonuria (PKU)
- Marfan Syndrome
- Porphyra Variegata
- Sickle Cell Anemia
- Fizzle Trait in Chickens
- Deafness in Blue-Eyed, Purely White-Coated Cats
With ___, where the affected individuals secrete an excessive quantity of amino acid phenylalanine in their urine, cerebrospinal fluid, and blood. They become short-stature, and mentally deficient, with widely spaced incisors, pigmented patches on the skin, excessive sweating, and with non-pigmented hairs and eyes.
Phenylketonuria
___ refers to a human malady resulting from an autosomal dominant mutation in the gene encoding the connective tissue protein fibrillin.
Marfan Syndrome