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PHRM 841 > IHD/HF Formulary Quiz > Flashcards

IHD/HF Formulary Quiz Flashcards

1
Q

Brand Name: Aspirin

A

Ecotrin (EC), Bayer Aspirin, Vazalore (liquid capsule)

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2
Q

Dosing: Aspirin

A

Loading Dose: 162-325 mg

Maintenance Dose: 81 mg

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3
Q

Adverse Effects: Aspirin

A

GI Bleeding

Intracranial/Extracranial Bleeding

Hypersensitivity

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4
Q

Brand Name: Atorvastatin

A

Lipitor

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5
Q

Dosing: Atorvastatin

A

40-80 mg (high intensity)

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6
Q

Adverse Effects: Atorvastatin

A

diarrhea

arthralgia

nasopharyngitis

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7
Q

Monitoring Parameter: Atorvastatin

A

lipid panel

hepatic transaminase levels

signs/symptoms of myopathy/rhabdomyolysis

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8
Q

Brand Name: Rosuvastatin

A

Crestor

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9
Q

Dosing: Rosuvastatin

A

20-40 mg (high intensity)

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10
Q

Adverse Effects: Rosuvastatin

A

myalgia

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11
Q

Monitoring Parameters: Rosuvastatin

A

lipid panel

hepatic transaminase levels

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12
Q

Brand Name: Clopidogrel

A

Plavix

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13
Q

Dosing: Clopidogrel

A

Loading Dose: 300 or 600 mg

Maintenance: 75 mg

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14
Q

Adverse Effects: Clopidogrel

A

bleeding (1% increase in major bleeding when added to ASA)

rash

diarrhea

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15
Q

Monitoring Parameters: Clopidogrel

A

signs of bleeding

hemoglobin and hematocrit periodically

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16
Q

Brand Name: Prasugrel

A

Effient

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17
Q

Dosing: Prasugrel

A

Loading Dose: 60 mg

Maintenance Dose: 10 mg daily

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18
Q

Adverse Effects: Prasugrel

A

bleeding (0.6% increase in major bleeding and 0.5% increase in life-threatening bleeding)

diarrhea

rash

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19
Q

Brand Name: Ticagrelor

A

Brilinta

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20
Q

Dosing: Ticagrelor

A

Loading Dose: 180 mg

Maintenance Dose: 90 mg BID

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21
Q

Adverse Effects: Ticagrelor

A

bleeding

bradycardia

heart block

dyspnea

1% risk of major bleeding

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22
Q

Monitoring Parameters: Ticagrelor

A

signs and symptoms of adverse effects

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23
Q

Brand Name: Pravastatin

A

Pravachol

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24
Q

Dosing: Pravastatin

A

40-80 mg

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25
Q

Adverse Effects: Pravastatin

A

musculoskeletal pain

upper respiratory tract infection

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26
Q

Monitoring Parameters: Pravastatin

A

lipid panel

hepatic transaminase levels

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27
Q

Brand Name: Simvastatin

A

Zocor

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28
Q

Dosing: Simvastatin

A

20-40 mg

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29
Q

Adverse Effects: Simvastatin

A

-atrial fibrillation
-edema
-eczema
-abdominal pain
-constipation
-gastritis
-nausea
-cystitis
-increased serum transaminases
-headache
-vertigo
-increased creatine phosphokinase in blood specimen
-myalgia
-bronchitis
-upper respiratory infection

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30
Q

Monitoring Parameters: Simvastatin

A

lipid panel

hepatic transaminase levels

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31
Q

Brand Name: Nitroglycerin

A

Nitrostat, Nitromist, Minitran

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32
Q

Dosing: Nitroglycerin

A

SL Tab: 0.3-0.6 mg prn repeat q5min 1-3 times

SL Spray: 0.4 mg/spray prn repeat q5min 1-3 times

SL Powder: 0.4 mg/pack prn repeat q5min 1-3 times

IV: 10 mcg/min IV

Patch: 0.2 - 0.4 mg/hour once daily, on for 12-14 hours, off for 10-12 hours

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33
Q

Adverse Effects: Nitrates

A

headache
hypotension
facial flushing
reflex tachycardia

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34
Q

Monitoring Parameters: Nitrates

A

Blood pressure

Heart Rate

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35
Q

Brand Name: ISMN

A

Monoket

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36
Q

Dosing: ISMN

A

Immediate Release: 20 mg BID (8 am 3pm)

Extended Release (SR): 30-60 mg once daily, may titrate to 120 mg

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37
Q

Brand Name: ISDM

A

Dilatrate-SR, Isordil Titradose

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38
Q

Dosing: ISMD

A

Immediate Release: 5-20 mg BID/TID initially, max 10-40mg BID/TID (14 hour nitrate free period)

Extended Release: 40-160 mg/day (18 hour nitrate free period)

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39
Q

Brand Name: Ranolazine

40
Q

Dosing: Ranolazine

A

500 mg BID (max 1000 mg BID)

41
Q

Adverse Effects: Ranolazine

A

Constipation

Nausea

Dizziness

Headache

42
Q

Monitoring Parameters: Ranolazine

A

QT interval

43
Q

Brand Name: Bisoprolol

44
Q

Dosing: Bisoprolol

A

5-10 mg QD

45
Q

Monitoring Parameters

A

BP
HR (50-60 bpm)

46
Q

Brand Name: Nebivolol

47
Q

Dosing: Nebivolol

A

5 mg daily (max: 40 mg daily)

48
Q

Brand Name: Propranolol

49
Q

Dosing: Inderal

A

80-160 mg daily

50
Q

Brand Name: Nifedepine

A

Procardia, Adalat, Cardene

51
Q

Dosing: Nifedepine

A

10-20 mg TID

20-40 mg TID (Cardene)

52
Q

Brand Name: Felodipine

53
Q

Dosing: Felodipine

A

5-10 mg daily

54
Q

Adverse Effects: DHP CCBs

A

hypotension

flushing

headache

dizziness

peripheral edema

reflex tachycardia

55
Q

Monitoring Parameters: DHP CCBS

A

edema

blood pressure

56
Q

Brand Name: Verapamil

A

Calan, Isopin

57
Q

Dosing: Verapamil

A

Immediate Release: 60-90 mg TID-QID

Extended Release: 240 mg daily

58
Q

Adverse Effects: Non DHP CCBs

A

reduced myocardial contractility (V>D)

bradycardia

AV Block (V>D)

Hypotension

Flushing

Headache

Dizziness

Constipation (V>D)

59
Q

Monitoring Parameters: Non DHP CCBs

A

constipation

heart rate

blood pressure

60
Q

Brand Name: Diltiazem

61
Q

Dosing: Diltiazem

A

80-120 mg TID

SR: 60-120 mg BID

CD: 180-360 mg

XR: 180-540 mg

ER: 180-360 mg

62
Q

Brand Name: Dapagliflozin

63
Q

Dosing: Dapagliflozin

A

5 mg PO QD (eGFR > 45)
max dose: 10 mg PO QD

64
Q

Brand Name: Empagliflozin

65
Q

Dosing: Empagliflozin

A

10 mg PO QD (eGFR > 30)
max dose: 25 mg PO QD

66
Q

Adverse Effects: SGLT-2

A

-UTIs
-genital fungal infections
-increased urination
-hypotension
-hyperkalemia
-increased cholesterol
-diabetic ketoacidosis
-bone fractures and decreased bone mineral density (canagliflozin)
-acute kidney injury (canagliflozin and dapagliflozin)

67
Q

Monitoring Parameters: SGLT-2s

A

-use with caution in patients who have potential for dehydration or hypotension or taking diuretics, NSAIDs, or ACE inhibitors/ARBs (canagliflozin and dapagliflozin)
-preventative foot care and monitor for new pain, tenderness, sores, ulcers, and infections in legs and feet
-use with caution in patients with prior amputations, peripheral vascular disease, neuropathy, and diabetic foot ulcers
-monitor signs and symptoms of tenderness, redness, or swelling of genitals or area from genitals to back of rectum, and fever, fatigue, and malaise

68
Q

Brand Name: Hydralazine

69
Q

Dosing: Hydralazine

A

25 mg TID in combination with ISDN
(target: 75 mg or 100 mg TID)

70
Q

Adverse Effects: Hydralazine

A

palpitations
tachycardia
chest pain
GI side effects
headache
hematologic dyscrasias
hepatotoxicity
lupus-like syndrome/rash
fluid retention

71
Q

Monitoring Parameters: Hydralazine

A

Blood pressure
HR
CBC
antinuclear antibody titer

72
Q

Brand Name: Furosemide

73
Q

Dosing: Furosemide

A

initial dose: 20-40 mg qd or bid

Maintenance: 20-160 mg qd or bid

74
Q

Adverse Effects: Loop Diuretics

A

AKI
Fluid/electrolyte imbalance
hypersensitivity
ototoxicity

75
Q

Monitoring Parameters: Loop Diuretics

A

BP
Electrolytes
Kidney Function
Fluid I/Os

76
Q

Brand Name: Bumetadine

77
Q

Dosing: Bumetadine

A

Initial Dosing: 0.5-1 mg qd or bid

Maintenance: 1-2 mg QD or BID

78
Q

Brand Name: Torsemide

79
Q

Dosing: Torsemide

A

Initial: 10-20 mg

Maintenance: 10-80 mg

80
Q

Brand Name: HCTZ

A

Esidrix, Hydrodiuril

81
Q

Dosing: HCTZ

A

initial: 25 mg/day

maintenance: 100 mg/day

82
Q

Brand Name: Clorthalidone

83
Q

Dosing: Clorthalidone

A

12.5-25 mg/day

maintenance: 50 mg/day

84
Q

Adverse Effects: Thiazides

A

hypokalemia
hypomagnesemia
hypercalcemia
hyperuricemia
hyperglycemia
hyperlipidemia
sexual dysfunction
increase in triglycerides/cholesterol

85
Q

Monitoring Parameters: Thiazides

A

BP
Fluid I/O
Serum Electrolytes
Kidney Function

86
Q

Brand Name: spironolactone

87
Q

Dosing: Spironolactone

A

Initial: 12.5 mg qd
Maintenance: 50 mg/day

88
Q

Adverse Effects: spironolactone

A

hyperkalemia
hyponatremia
gynecomastia (aldosterone)

89
Q

Monitoring Parameter:

A

electrolytes
potassium
blood pressure

90
Q

Brand Name: Candesartan

91
Q

Dosing: Candesartan

A

initial: 4-8 mg qd
target: 32 mg qd

92
Q

Brand Name: Digoxin

93
Q

Dosing: Digoxin

A

0.125-0.25 mg once daily

94
Q

Monitoring Parameters: Digoxin

A

Serum Concentration 0.5 - <0.9 ng/mL
HR Rhythm
electrolytes

95
Q

Adverse Events: Toxicity

PHRM 841 (2 decks)

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