Idt 5 Flashcards
Ergots target what
5HT partial agonist
D2/D3 partial agonist
How is sumatriptan metabolized and what does this mean for DDI
MAOA
Do not take with MAOI
Which triptans can be taken with MAOI and why
Naratriptan
Frovatriptan
Eletriptan
Amine-ring blocks MAOA
Which triptan has half life of over a day?
Frova
Gepants should not be taken with what
3A4 inhibitor or inducers
Gepants MOA
CGRP receptor antagonist
Gepants should have what in order to resemble what
Amide linkages
To resemble peptide bonds
Which triptans are odt
Riza
Zolmi
Nasal triptans
Suma
Zolmi
Which triptans have delayed onset
Frova
Nara
Ergot alkaloids must be used along with
Antiemetics
Chlorpromazine
Prochlorpromazine
Metoclopramide
Why is lasmiditan safe in CVD
Lacks vasoconstriction
Lasmiditan often causes
Dizziness and drowsiness
Migraines and COCs
Should be avoided
The dose is lower now
But progestin only birth control is available
Cluster headache can be treated with
O2
SSRI
Triptan nasal or IV
IN lidocaine if triptan CI