IDS Flashcards
organisms which cause diarrhea via pre-formed toxins (3)
organisms which cause diarrhea via cytotoxins (2)
organisms which cause diarrhea via entero toxins (4)
The most clinically important flaviviruses that cause the fever and myalgia syndrome are
Dengue viruses causing breakbone fever
Most important of the parasitic diseases of humans,
Malaria
organisms causing filariasis (2)
- Wuchereria bancrofti
- Brugia malayi
malaria species with Malignant vs Benign Tertian periodicity
malarial species with banana-shaped gametocytes
malaria species with preference to:
* young
* old
* both young and old
malarial species with band or rectangular forms of trophozoites
malarial species with irregularly shaped large rings and trophozoites; Schuffner dots
malarial species with enlarged and oval with tufted ends Schuffner dots
malarial species associated with cerebral malaria
P. falciparum
malarial species with tendecny to relapse
P. vivax
P. ovale
relapse in malaria is due to reactivation of what malaria stage
hypnozoites
When a patient in or from a malarious area presents with fever, what should be done to confirm diagnosis and identify species of infecting organism?
Thick and thin blood smears
What is blackwater fever?
Acute hemolytic anemia with massive hemoglobinuria in malaria
Highest endemicity of malaria in
(MIMAROPA region) Palawan
Hallmark features of enteric fever
- Fever and abdominal pain
Enteric fever is a misnomer in that hallmark features are variable
rose spots or faint, salmon-colored, blanching, maculopapular rashes located primarily on the trunk and chest are found in what disease
enteric fever
Term for the neuropsychiatric symptoms with picking at bedclothes or imaginary objects in patients with enteric fever
Muttering delirium or coma vigil
Risk factors for chronic carriage in patients with
- Women
- infants,
- persons who have biliary abnormalities or concurrent bladder infection with Schistosoma haematobium
Most effective class of agents in treatment in enteric fever
fluoroquinolones
Most severe form of leptospirosis
Weil’s Syndrome ( characterized by jaundice, renal dysfunction, and hemorrhagic diathesis)
Severe leptospirosis should be treated with what medication
IV Penicillin
Prophylaxis for leptospirosis exposure
Doxycycline
Differentiate the ff in terms of mode of transmission :
*Schistosoma japonicum
* Paragonimus westermani
* Clonorchis sinensis
Differentiate the ff in terms of body part affected :
*Schistosoma japonicum
* Paragonimus westermani
* Clonorchis sinensis
Differentiate the ff in terms of mode of intermediate hosts :
*Schistosoma japonicum
* Paragonimus westermani
* Clonorchis sinensis
Differentiate the ff in terms of drug of choice :
*Schistosoma japonicum
* Paragonimus westermani
* Clonorchis sinensis
Intermediate host of S.japonicum
Oncomelania quadrasi (snail)
Intermediate host of P. westermani
Sundathelphusa philippina (mountain crab)
Symptomatic acute schistosomiasis usually seen in travelers who have contracted the infection (schistosomiasis) for the first time
Katayama fever
schistosomiasis is most prevalent in what province
Oriental Mindoro
Mainstay in tbe control program of schistosomiasis in the Philippines
Mass treatment with praziquantel
Clostridium tetani are anaerobic, gram negative, spore-forming rods
True or False
False
gram POSITIVE dapat
Most characteristic pathologic finding in rabies
Negri bodies
term for the eosinophilic cytoplasmic neurons that are composed and viral RNA in rabies
Negri bodies
Examples of bacteriostatic antibiotics (6)
Examples of bactericidal antibiotics (6)
Example of 1st gen cephalosporin (1)
Example of 2nd gen cephalosporin (2)
Example of 4th gen cephalosporin (1)
Example of 3rd gen cephalosporin (4)
Example of 5th gen cephalosporin (1)
Protein synthesis inhibitor that causes gray baby syndrome
Protein synthesis inhibitor that causes tooth enamel discoloration
only Protein synthesis inhibitor that binds to 30S subunit
Protein synthesis inhibitor that causes pseudomembranous colitis
clindamycin
aminoglycoside that is absolutely contraindicated in myasthenia gravis due to its side effect (neuromuscular blockade)
gentamicin
aminoglycoside that has pseudomonal coverage and has narrow therapeutic window
aminoglycoside used for treatment of drug-resistant gonorrhea
aminoglycoside used for treatment of hepatic encephalopathy (2nd line)
neomycin
FQ that causes tendonitis or tendon rupture in people > 60 y/o and in patients taking prednisone
Example of 2nd, 3rd, vs 4th gen cephalosporin
FQ used for UTI and GIT infections
FQ used for pulmo infections
FQ used for ocular infections
most hepatotoxic TB meds
TB med that causes peripheral neurotoxicity
anong klaseng color-blindness ang dinudulot ng ethambutol
red-green color blindness
top 3 hepatotoxic anti TB meds
pyrazinamide
rifampicin
isoniazid
leprosy drug that causes methemoglobinemia and hemolysis if px is G6PD deficient
Dapsone
leprosy drug that causes red-orange urine
leprosy drug that causes red-black discoloration that accumulates esp in lesional areas
Clofazimine
antibiotic used to treat pseudomembranous colitis
metronidazole
antibiotic which cause disulfiram-like reaction when taken with alcohol
metronidazole
Nitrofurantoin causes this pulmonary complication
pulmonary fibrosis
antifungal used as topical treatment for dermatophytosis and candidiasis
Ketoconazole
antifungal that causes gynecomastia as side effect
antifungal used for prophylaxis and treatment of candidiasis and cryptococcosis
acyclovir is used to treat what 2 viruses
antiviral that causes obstructive crystalline nephropathy and AKI if not adequately hydrated
ganciclovir is used to treat what virus (1)
Foscarnet is used to treat what 3 viruses
antiviral which causes cerebellar dysfunction and livedo reticularis
Amantadine
antiviral that is used as treatment and prevention of influenza A and B
antiviral used as treatment of hepatitis B infection and HIV
Lamivudine
antiviral used as treatment of hepatitis C and RSV infection
Ribavirin
examples of NNRTI (3)
anti malarial drug that causes retinopathy
anti malarial drug that causes cinchonism
quinine
anti malarial drug that should not be given in pregnant patients
Primaquine
anti malarial drug that is the DOC for eradication of hypnozoites of P. vivax and ovale to eradicate persistent liver stages and prevent relapse
Primaquine
Only anti malarial drug advised for pregnant women traveling to areas with drug-resistant malaria
Mefloquine
anti malarial drug that is generally considered safe in the second and third trimesters of pregnancy
Mefloquine
anti malarial drug used as prophylaxis in areas with chloroquine- or mefloquine-resistant P.falciparum
Doxycycline
Drug of choice for all patients with severe malaria everywhere
Artesunate
Should be used in pregnant women with severe malaria
- DOC for asymptomatic cyst carriers of E. histolytica
- Luminally active agent used to eradicate the cysts of£. histolytica
DOC for Cryptosporidium parvum infection
DOC for
* Amoebic dysentery
* Trichomoniasis
* Giardiasis
DOC for Pneumocystis jirovecii pneumonia
DOC for Toxoplasmosis
DOC for African sleeping sickness
DOC for Chagas disease
DOC for Leishmaniasis
anti-helminthic drugs which inhibit helminthic microtubules (2)
albendazole, mebendazole
Treatment for echinococcosis, intestinal parasitic nematodes
albendazole
Drug of choice for filarial disease and Loa loa
DEC
Considered more effective than albendazole for Strongyloides
First line agent for onchocerciasis
Side effect of this anti-helminthic drug is Mazzotti reaction
Used in Enterobius infection
Drug of choice for trematodes and cestodes;
EXCEPT echinococcosis (because it is treated with albendazole)
Back-up drug to Praziquantel