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Identification Flashcards

1
Q

Variation in shapes of RBC

A

Poikilocytosis

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2
Q

Variation in sizes of RBC

A

Anisocytosis

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3
Q

Leukoerythroblastosis is not associated with ______

A

Erythroblastosis fetalis (HDN)

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4
Q

Procedure employs blood w/ EDTA diluted with 0.105 M NaCitrate or NSS

A

Modified Westergren

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5
Q

What is the T-cell growth factor and mast cell activating factor effect in stimulating erythroid and myeloid proliferation

A

Interleukin-9 or IL-9

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6
Q

Largest of all hematopoietic stem cells

A

Polypoid megakaryocyte

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7
Q

Which among RBC has figure of 8, loop shape

A

Cabot ring

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8
Q

Which among cells is the earliest erythroid recognizable precursor

A

Pronormoblast

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9
Q

Which of the ff mononuclear cells are w/o specific cytoplasmic granules

A

Lynphocytes

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10
Q

Which ff cell is larger than monocyte w/ irregular cell membrane with blunts and pseudopods

A

Megakaryoblast

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11
Q

Common precursor for granulocytes, monocytes, erythrocytes and megakaryocytes

A

Myeloid stem cells

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12
Q

Rbc thinner than normal, peripheral rim of hemoglobin w/ dark Hgb containing area

A

Leptocytes

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13
Q

Disintegrating RBC

A

Leptocytes

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14
Q

Cell that has deep purple and paler nucleus which often nearly hidden by granules

A

Basophils

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15
Q

Last nucleated cell

A

Orthochromic normoblast

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16
Q

Hematopoietic stem cells also known as CFU-GEM expresses

A

CD34/CD33

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17
Q

Large cell w/ single eccentric nucleus has reticular chromatin and prominent nucleolus

A

Osteoblast

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18
Q

Promotes differentiation and maturation of
megakaryocytes

A

Thrombopoietin

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19
Q

Nutritional deficiency of Cobalamine, due to failure of gastric mucosa produce intrinsic factors

A

Pernicious anemia

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20
Q

During fetal life, all Rbc produce HbF, in adults, 0.2-7% are HbF

A

True

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21
Q

Reticulocytopenia and ABN RBC are primary findings, ABN granulocyte are rare and less than 1% blast cells

A

Refractory anemia

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22
Q

Acute myelocytic leukemia seen in

A

M4

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23
Q

Earliest Thrombopoiesis w/ overlapping lobe and small amount of basophilic cytoplasm

A

Megakaryoblast

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24
Q

Degrades fibrin clot and retract fibrinogen forms FDP

A

Plasmin

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25
Content of eosinophilic specific granules toxic to parasite that neutralize heparin and release histamine
Major basic protein
26
Autosomal dominant that failure normal segmentation of neutrophils:
Pelger-huet anomaly
27
AML w/ minimal differentiation
M0
28
A molecule of Hgb is consist of ___ polypeptide chain
2
29
A mixture of oxidized denatured Hgb during oxidative hemolysis
Sulfhemoglobin
30
Principle involved in automated counting
Electric impedance
31
Measures fibrin clot from activation of F7 to fibrin stabilizing clot:
PT
32
Measures fibrin clot from activation of F7 to fibrin stabilizing clot:
Myocosis fungoides
33
Global test adequacy of primary hemostasis
Template bt
34
Activator that initiates the fibrinolysis and convert plasminogen to plasmin -
t-PA
35
Primary test in diagnosis of hairy cell leukemia
ACP
36
Decrease function of F2, 7, 10 (Protein C, Protein S)
Warfarin
37
Prolonged pt and normal ptt seen in patients with deficiencies in which factor in intrinsic factor
8,9,11,12
38
Prolonged pt and normal ptt seen in patients with deficiencies in which factor in extrinsic factor
7
39
Cofactor of required in activation of F2 by activated F8
5
40
Diluting fluid in platelet count in phase contrast
1%NH4Oxalate
41
In phase contrast microscope, how many squares in platelets in improved neubauer
25 small squares
42
Light angle scatter in laser-based cell counting chamber is used to measure
cytoplasmic granularity
43
Patients with infectious mononucleosis, this blood cell is infected
B-lymphocyte
44
Inhibits factor 2,9,7,11,10, enhances the activity of anti- thrombin as natural anticoagulant
Heparin
45
Which of the ff not function of spleen as hematopoietic origin
Secretion of mitogen
46
Immature non-nucleated RBC with RNA granules
Reticulocytes
47
Not associated with sickle cell
Promotes spleen destruction
48
Tissue extract with phospholipid and tissue factor that activates F7 in extrinsic pathway
Thromboplastin
49
An 18- Kda produce by activated T-cell and mast cell
IL-4
50
General measure in extrinsic and common pathway
PT
51
General measure in intrinsic and common pathway
PTT
52
Condition of panmyelosis with increase megakaryocytes, granulocytes, erythrocytes
Polycythemia Vera
53
Provides initial hemostasis due to injury
Platelet plug
54
Platelet survival
8-11 days(in vivo) 3-5 days(in vitro)
55
Water soluble complex of ferric salt and protein
Ferritin
56
Production of azurophilic granules
Promyelocyte
57
Last stage of granulocytic that capable of mitosis
Myelocyte
58
HgB constituent that may degraded and return to amino acid pool
Globin
59
Cytokines produced by macrophages and kupffer cell
IL-18
60
Not considered myeloproliferative disorder
AML
61
Average concentration HgB in a given RBC
62
Factor 8 deficiency
Hemophilia A
63
Abnormal RBC due to abnormal radium potassium ratio in the RBC
Stomatocytes
64
Majority of iron bound to _____ which has capacity to bind 331 mg of iron/dl
Transferrin
65
Hematopoiesis begins at the 6th week of fetal life
Liver
66
Life span of basophil in bone marrow
Seven days
67
Sensitive test in folate or cobalamine deficiency. Measures ability of marrow cells in vitro to utilize deoxyuridine in DNA synthesis
Deoxyuridine suppression test
68
Chronic progressive panmyelosis characterized by triad findings vary in fibrosis in the marrow, splenomegaly and leukoerythroblastic anemia
Myelofibrosis w/ myeloid metaplasia
69
Useful in identifying w/ Beta-Thalassemia trait that elevated upto 7%
HbA2
70
This altered of immune response against host own immune system that produce Antibody against itself:
Autoimmune hemolytic anemia
71
Use to connote the appearance of neoplastic cell w/ non-hodgkins lymphoma
Lymphosarcoma cell leukemia
72
Rare autosomal dominant shows pale blue inclusion resembling Dohle bodies
May hegglin anomaly
73
Not required for RBC production
Folic acid Iron Protein Vitamin E
74
Normal Retic Count at birth
3-7%
75
Which of the ff refers to total red cell mass
Absolute polycythemia vera
76
This are the Pro-Tcell markers except?
CD3, CD 7, CD2, CD17
77
Term used if RBC is hypochromic and normochromic:
Anosochromia
78
Normal value of reticulated platelet count
3-20%
79
Variety of Acute leukemia predominant blasts cannot classify using morphologic, cytochemical, ultrastructural and immunologic or DNA analysis
Acute undifferentiated leukemia
80
Hgb not denatured by alkaline solution
HbF
81
Fastest Hgb at pH 8.4 in alkaline medium
HbH
82
Which of the ff also called CSF-1
Monocyte macrophage CSF
83
Genetically impairment of globin synthesis
Thallasemia
84
Reveals pancytopenia, decrease hematopoietic cell lines resulting to low all blood levels
Aplastic anemia
85
1 g of Hgb carries ___ mg of Iron
3.47
86
Abundant blue cytoplasm, eccentric round nucleus w/ light vacuoles w/ well defined golgi zone adjacent to nucleus
Plasma cell
87
Bilobed structure which recognized by size and bright red granules
Eosinophil
88
Young cells w/ residual RNA polychromatophilic RBC in air dried film stained with __?
Brilliant cresyl blue New ,methylene blue
89
Quantitative measure of Carboxy Hgb
Either (Differential spectrophotometer, gas chromatography)
90
Absorbance of spectrophotometer for determining Hgb using HCN
540 nm
91
Conjugated protein serves as a vehicle of oxygen and carbon dioxide
Hgb
92
Lab findings of DIC:
(increase D-dimer, increase PT/PTT, decrease platelet count)
93
Result of PT & PTT mixing studies: mixed plasma is normal, after 1-2 hrs it is prolonged, suggestive of
Presence of FVIII inhibitor
94
Cooper Cruick Shank method is for:
Absolute neutrophil count
95
Pathway using 2,3-BPG
Rapaport-Leubering Shunt

Hematology (2 decks)

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