ID treatments Flashcards
What is empiric antibiotic tx for TSS?
Clindamycin + Vanco
(Also needs rapid rehydration–> 3L)
What type of abx should be used to tx SSSS? If there is no response, what 2 meds should you consider?
- Penicillinase-resistant beta-lactam agents (Nafcillin)
- If no response, consider MRSA & tx with vancomycin
How do you tx anthrax if it is systemic w/ meningitis?
- Report/consult public health department
- Cipro + meropenem + Linezolid
- Antitoxin
- etc.
How do you tx Anthrax that is systemic WITHOUT meningitis?
- Report/consult public health department
- Cipro + Clinda
- Antitoxin
- etc.
How do you treat cutaneous Anthrax?
- Report/consult public health department
- _Ciprofloxacin**_
- Antitoxin
- etc.
***definitely know abx- will be on exam***
What is post-exposure prophylaxis for patients exposed to aerosolized B. anthracis (anthrax)?
Start Cipro w/in 48hrs- treat for 60 days
+
3 dose series of Anthrax vaccine
How do you prevent rabies? (this is the main tx)
Immunize household pets and ppl w/ signifcant animal exposure
What is tx for Zika virus?
rest
symptomatic tx
How do you tx legionella?
Azithromycin or clarithromycin or levofloxacin x10-14days
No isolation needed
How do you tx pontiac fever?
symptomatic tx
How do you tx Botulism?
- Equine serum heptavalent botulism antitoxin w/in 24 hrs
- intubation
- IV fluids
How do you treat diphtheria? (4)
- Diphtheria equine antitoxin
- Penicillin or erythromycin x14 days
- Remove membrane by laryngoscopy
- ISOLATION until neg culture x3
How do you tx tetanus? (7 most important)
- ICU
- Metronidazole
- Tetanus immune globin
- Tetanus immunization x3
- Benzos
- airway management
- neuromuscular blocking agents
How do you tx Lyme Disease? Alternative tx for pregnant women?
Doxycycline x10-14 days
Amoxicillin for pregnant/lactating women
How do you tx Rocky Mountain Spotted fever?
Doxycycline w/in 5 days of onset
What are the 2 main treatments of infectious mononucleosis caused by EBV?
- Supportive care- NO ABX (Amox)
- Sports restrictions- no contact b/c of splenomegaly
How do you tx cytomegalovirus
strong antivirals (ex: ganciclovir)
Although most pts with Toxoplasmosis don’t need treatment, If someone has severe/prolonged infection, or are immunocompromized/pregnant?
- Pyrimethamine + sulfadiazine OR pyrimethamine + clindamycin + leucovorin
- Tx minimum of 2-4 weeks
- Ophthalmology
What is prophylactic treatment of Toxoplasmosis?
Trimethoprim- sulfamethoxazole
How do you treat Cryptococcosis?
- Amphotericin B x 14 days
- Follow with fluconazole x 8 weeks
When would you treat VZV and what would you tx with?
Acyclovir w/in 72 hrs of onset
>72 hrs if still getting new lesions
if immunocompromised
How would you tx a pt w/ VZV with mild pain
NSAIDs and acetaminophen
How would you tx a pt w/ VZV with mod-severe pain
Stronger opioid (Oxycodone, morphine)
