ID- Flu + COVID Flashcards

1
Q

What is one way to transmit flu

A
  1. Droplets MAINLY
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2
Q

Which type of influenza experiences a greater drift?

A

Influenza A

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3
Q

What are symptoms/diagnosis of influenza

A

sudden onset
- fever
- cough
- chills/sweat
- malaise/fatigue
- myalgia

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4
Q

How long does flu last (excluding fatigue)

A

7-10 days

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5
Q

When are the patients eligible for PCR testing

A
  • Sick <18 yrs in ER
  • Sick hospitilized patients
  • Sick residents of LTC
  • First 4 individuals in an outbreak setting
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6
Q

Who can take Oseltamivir

A

uncomplicated flu 1+ who have been ill NO MORE THAN 2 DAYS
- pregnant people

Or complicated illness (even after 2+days)

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7
Q

What is the benefit of oseltamivir (efficacy)

A
  • decreases mortality in hospitalized patients
  • decreases symptomatic transmission
  • shortens symptom duration BY 1 DAY
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8
Q

When does benefit outweigh harm for oseltamivir

A

When they are at risk for complications

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9
Q

When can you give zanamivir

A

7+
Powder
- Known influenza B
- Failed oseltamivir prophylaxix
- not responding to oseltamivir
- Oral not possible

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10
Q

What are risk factors for complications of flu?

A
  • Age less than 5 or 65+
  • LTC residents
  • DIABETIC
  • indigenous
  • immunosuppresion
  • OBESITY
  • chronic renal insufficiency
  • Asthma or COPD
  • pregnant people and up to 4 weeks post birth
  • CV diseases (except hypertension)
  • neurological disease
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11
Q

How to treat adult with no risk factors?

A

within 48 hours
- consider therapy

48+ hours
- NOT recommended

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12
Q

How to treat adult with risk factors?

A

within 48 hours:
- start therapy

48+ hours
- consider therapy

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13
Q

How to treat adults with moderate, progressive, severe or complicated illness?

A

START therapy right away

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14
Q

What are red flags in ADULTS?

A
  • seizure
  • not urinating
  • severe muscle pain
  • severe weakness
  • difficulty breathing
  • confusion
  • dizziness
  • twice sickening
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15
Q

How to treat a child with mild disease and no risk factors?
<1yr
1-5yrs
5+ years

A

<1yr
- not approved

1-5yrs
- consider therapy if within 48 hours

5+ years
- not given

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16
Q

How to treat a child with mild disease and risk factors?

A

Give therapy immediately (no need to wait 48 hour)

17
Q

How to treat children with moderate, progressive, or severe influenza

A

start therapy

18
Q

What are red flags for infants and children

A
  • fever with rash
  • bluish skin colour
  • confusion
  • being so irritable
19
Q

When is chemoprophylaxis for flu indicated? Can you give it to close contacts?

A

oseltamivir can decrease symptomatic transmission
When there is a risk for an outbreak in hospital or LTC
- when you need to “bridge” until vaccine becomes effective

Can you give it to close contacts?
No, early therapy is better

20
Q

What is the dose for oseltamivir treatment and chemoprophylaxis?

A

Treatment:
- 75 mg TWICE daily for 5 days

chemoprophylaxis
- 75 mg once daily for 10 days

21
Q

What is the dose for zanamivir treatment and chemoprophylaxis?

A

Treatment
- 10 mg twice daily (2 5 mg inhaltions) for 5 days

chemoprophylaxis
- 10 mg once daily for 10 days

22
Q

How is covid transmitted

A

Primarily with droplets
- aerosols and fomites play a role

23
Q

What are risk factors for severe COVID-19 (3)

A
  • 60+yrs
  • under-immunized
  • 1+ comorbidity
24
Q

What are red flags of covid-19

A
  • hypotension
  • blue lips or face
  • coughing up blood
  • tachypnea
  • reducing O2 saturation
25
Q

What is the eligibility for paxlovid (5)

A

One of these only:
- 60+yrs
- under-immunized
- 1+ comorbidity
- groups with poorer outcomes due to social determinants

Requires a positive test and within 5 days symptoms

26
Q

What is the MOA of paxlovid? efficacy (1)

A

block viral replication
Efficacy
- decreased hospitlization and death

27
Q

When is Paxlovid NOT indicated

A

no new or increased supplemental oxygen needs

28
Q

When would you give remdesivir

A

if they have hypersensitivity to paxlovid or greater than 5 days onset
- has to be within 7 days

29
Q

How long do post-covid symptoms last? What are they

A

can last and get new symptoms 12+ weeks
- fatigue
- cough