Antimicrobial Spectra Flashcards
Which bacteria has B-lactamase as the main mechanism of resistance to penicillins
Staph aureus
Enterococcus faecalis
Gram negatives
Oral Anaerobes
Which penicillin would you give for P. Aeruginosa?
Piperacillin or piperacillin-tazobactam
Which penicillin is has coverage for S. pneumo
All penicillins
Which penicillin has coverage for H. influ
All except cloxacillin
What penicillins cover Staph aureus (MSSA)
cloxacillin (VERY NARROW COVERAGE)
- amoxi-clav
- piperacillin-tazobactam
Which cephalosporin covers Staph aureus (MSSA)?
1st gen
2nd gen
3rd gen ONLY ceftriaxime and ceftazidime
Which cephalosporin has H. flu coverage?
All
Which cephalosporin has S. pneumo coverage?
All except ceftazidime (last one)
Which cephalosporin has coverage against Pseudo aeruginosa?
Ceftazidime
What do all cephalosporins NOT cover?
- Atypicals
- MRSA
- any enterococcus
What is the trend for gram-negative coverage in cephalosporins
as generation increases, gram-negative potency increases
Differentiate between coverage of ertapenem and other carbapenems
Ertapenem loses coverage for E. faecalis and Pseudomonas
Both do not touch E. faecium and atypicals
What does vancomycin cover generally?
ALL gram positive
- cannot penetrate outer -membrane of gram-neg
Which protein-synthesis does not cover H. infly
Clindamycin
What respiratory FQ is best coverage for S. pneumo
levofloxacin
moxifloxacin
