ID Exam 2: Anaerobic

Question 1

Basis of O2 tox for anaerobes

Answer 1

Direct oxidation
Production of H2O2 and superoxide (no enzymes to breakdown)
Lack catalase and dismutase

Question 2

Will strep and enterococcus grow under anaerobic conditions?

Will E coli and staph grow under anaerobic conditions?

Answer 2

Strep/enterococcus will

E coli and staph will grow, not as well

Question 3

Formation of anaerobic abcess

Answer 3

Acute: aerobic/faculatative organisms dominate -> febrile, hypotensive

Chronic: Fibrin-encased abscess, anaerobes, polymicrobial

Question 4

Bacteroides fragilis

Answer 4

Normal gut flora
Common in anaerobic abscesses especially below diaphragm
Aerotolerant, encapsuled
Trauma, perf, colon CA, -itis

Question 5

Maternal and neonatal tetanus

Answer 5

Infection post partum, usually of umbilical cord
Preventable with vaccine
More common abroad, fatality 80%
Vaccine, hygiene, clean cord practice

Question 6

Food born botulinum vs. infant/wound?

Answer 6

Preformed toxin compared to local production

Question 7

Botulinum toxin as bioweapon

Answer 7

Can be aerosolized toxin (not the bugs)