ID Flashcards
Bacterial meningitis empiric treatment
?hospital-acquired
Vanc/ceftriaxone (or cefotax)
+ amp (>50 yo)
If hospital acquired, then cefepime or merrem instead of 3rd gen ceph
Encephalitis + ovarian teratoma (50%)
Psych symptoms
Seizures
Autonomic instability
Anti-NMDA R encephalitis
Skin ulcer, evolve from painless nodules, in neutropenic patient
Pseudomonas (ecthyma gangrenosum)
Empiric tx for non-purulent and purulent cellulitis
- Dicloxacillin, cephalexin, clinda
2. Bactrim, clinda, doxy, minocycline, linezolid (iv vanc if bad)
Nec fasc treatment
Vanc
Imipenem
Clindamycin
Debride
Abscess < 5 cm treatment
I&D only
Bat & bird droppings
Histo
Rabbits
Franciscella
Bird exposure
Chlam. Psittaci
Pseudomonas RFs
Bronchiectasis
Pred > 10
Broad abx > 7 days in preceding month
Malnutrition
Tick bite
Fever
Lymphocytic meningitis
Petechial rash
Dx & Tx
RMSF
Doxycycline
Can have negative antibodies
Tick bite
Erythema migrans
Meningitis
Dx & Tx
Lyme
Doxycycline
HIV
Fever,chills,sweats,weight loss after starting therapy
LAD, HSM, anemia, leukopenia, increase ALP
Dx & Tx
DMAC and IRIS
Clarithromycin, ethambutol
Coccidioides meningitis
Tx
Fluconazole
Second - itraconazole
(Caspo does not penetrate CSF)
Neurosyphilis concerns
Next step…CSF or treat?
CSF studies
If positive, then IV PCN
TB treatment duration - reasons to prolong
2 mo initiation phase
4 mo continuation
7 mo continuation if:
No pyrazinamide
Cavitation and + sputum after initiation
Once weekly INH and rifapentamine and + sputum after initiation
5 mm positive PPD
10 mm positive PPD
15 mm positive PPD
Recent exposure
HIV +
Fibrotic changes on XR c/w old TB
Immunosuppressed > 15 mg pred for 4 weeks
IVDU Homeless, prisons, LTAC Recent immigration from country with high prevalence Lab personnel Hospital workers
Anyone
Post-exposure PPx for HIV
Pre-exposure PPx
Tenofovir-emtracirabine + raltrgravir
Tenofovie-emtracitabine
Late complement deficiency
Recurrent meningococcal meningitis, gonococcal infections
CVID
Recurrent sinusitis, pneumonia