ID Flashcards

1
Q

LRTI causes

A

Viruses = COVID-19, influenza, RSV, parainfluenza

  • viral pneumonia = widespread patchy appearance CXR + diffuse pneumonitis

Bacteria = strep/klebsiella pneumoniae, haemophilus influenzae

  • cough, purulent sputum, pain when breathing in, pleural effusion

Atypical bacteria = M. pneumoniae, legionella

  • diffuse picture

Tuberculosis

  • chronic picture, haemoptysis
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2
Q

LRTI Mx

A

Sampling + imaging

Oxygen

Fluids

Physiotherapy (chronic lung disease)

Abx:

  • amoxicillin
  • co-amoxiclav
  • cephalosporins
  • macrolides (azithro, clarithro, erythromycin = community, penicillin allergy, mainstay tx for atypical bacteria e.g. mycoplasma and legionella)
  • tetracyclines (rescue pack for COPD)
  • fluoroquinolones (levofloxacillin = hospital, penicillin allergy)
  • co-trimoxazole (hospital)
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3
Q

severity assessment for pneumonia

A

Confusion MTS<8

Urea >7mmol/l

RR >30/min

BP (<60mmHg diastolic, <90mmHg systolic)

Age >65

  • 0-1 low risk (<3% mortality) HOME tx
  • 2 medium risk (3-15% mortality) ADMIT to hospital (short stay inpatient, hospital supervised outpatient)
  • 3-5 high risk (>15% mortality) IV abx, supportive care, admit to ICU
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4
Q

UTI

A

cystitis

lower UTI

pyelonephritis

renal abscess

pain, fever, frequency, dysuria

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5
Q

Causes of UTI

A

E.coli, enterococcus, Group B strep, Klebsiella sp, proteus, other coliforms, candida

women>men

age

abnormal renal tract

urinary catheter

dehydration

calculi (more in neonates, cancer and obstruction of urinary tract)

diabetes

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6
Q

UTI mx

A

sampling and imaging (exclude renal abscess e.g. severe pyelonephritis and not improving)

fluids

obstruction removal

prevention

Abx:

  • nitrofurantion
  • trimethoprim
  • amoxicillin (preg)
  • cephalosporin (preg)
  • pivmecillinam
  • fosfomycin
  • fluoroquinolones (ciprofloxacin) = pyelonephritis
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7
Q

skin and soft tissue infections (SSTI)

A

impetigo

  • common and highly contagious skin infection that mainly affects infants and young children.
  • Impetigo starts with red sores or blisters, but the redness may be harder to see in brown and black skin. The sores or blisters quickly burst and leave crusty, golden-brown patches. The patches can: look a bit like cornflakes stuck to your skin.

erysipelas

  • an infection of the upper layers of the skin (superficial). The most common cause is group A streptococcal bacteria, especially Streptococcus pyogenes. Erysipelas results in a fiery red rash with raised edges that can easily be distinguished from the skin around it.

cellulitis

  • cellulitis makes your skin painful, hot and swollen. The area usually looks red, but this may be less obvious on brown or black skin.
  • Your skin may also be blistered, and you can also have swollen, painful glands.

infected ulcers/wounds

myositis

necrotising fasciitis

  • Early symptoms can include: a small but painful cut or scratch on the skin, intense pain that’s out of proportion to any damage to the skin, a high temperature (fever) and other flu-like symptoms
  • After a few hours to days, you may develop: swelling and redness in the painful area – the swelling will usually feel firm to the touch, diarrhoea and vomiting, dark blotches on the skin that turn into fluid-filled blisters
  • can lead to TOXIC SHOCK SYNDROME

redness, pain, heat, swelling

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8
Q

bacteria for SSTI

A

staph aureus = cellulitis, resistance to flucoaxcillin

streptococcus pyogenes = necrotising fasciitis

streptococcus dysgalactiae

pseudomonas = gram -ve, cellulitis, water activities, in diabetes and immunosuppression

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9
Q

mx of SSTI

A

sampling and imagin

debridement = ulceration, diabetic wound

tx underlying cause

elevation = lymphatic drainage

abx:

  • flucloxacillin
  • clindamycin
  • tetracyclines
  • co-trimoxacole
  • vancomycin
  • daptomycin
  • linezolid
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10
Q

febrile patient clinical evaluation

A

raised temperature?

infection? if yes, what/where is it?

will it kill them if I do not do anything soon?

  • severity = sepsis recognition and mx
  • site = critical organs e.g. pneumonia with resp failure, meningitis
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11
Q

what is sepsis?

identifying sepsis

A

life threatening organ dysfunction from dysregulated host response to infection

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12
Q

identifying sepsis = high, moderate-high, low risk criteria

A
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13
Q

sepsis screening tool

A
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14
Q

sepsis six

A
  1. high flow O2 = via non-rebreathe mask
  2. take blood cultres = and consider source control
  3. give IV abx = according to local protocol
  4. start IV fluid resuscitation = Hartmann’s or equivalent
  5. check lactate
  6. monitor hourly urine output = consider catheterisation

WITHIN 1 HOUR

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15
Q

ID Hx: sx

A

fever = how long, when did it start, sweats/rigors and shivering, recorded?

rash = patches, spots, skin colour/erythema

sore throat, sore eyes, swollen glands (mucus membranes) =

weight loss, anorexia

respiratory = sputum, blood

GI tract = abdo pain, diarrhoea (watery, darker, blood), vomiting

urogenital = dysuria, colour, smell, frequency, discharge (period with women)

localised pain = joint pain (arthritis), general myalgia (dengue, influenzae), headache /neck stiffness(CNS)

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16
Q

ID Hx: fever

A

infective

viral

  • CMV can be 3 weeks
  • EBV

bacterial

  • typhoid 10-14 days
  • abscesses (few months)
  • endocarditis (few months)
  • brucellosis (bone/joint + travel)

toxoplasmosis

fungal infection but very unusual

non-infective

  • cancer esp lymphoma
  • connective tissue disease SLE, PMR
  • multiple pulmonary emboli
  • haematoma/infarcted tissue
  • drug fever e.g. abx
17
Q

ID Hx: exposure

A

travel

  • return-sx onset
  • duration of trip
  • reason for trip
  • who travelled
  • accomodation
  • prophylaxis
  • exposures as below

contact

water

kids

animal/pets

surgery, trauma, implants

injecting drug use

18
Q

ID Hx: Past ID hx

A

routine vaccination

hx

longer term travel hx

abx hx (what and when)

TB (self or family)

pneumonia, hepatiis

STD history/testing

sexual partner(s)

injecting drug use

19
Q

incubation periods worth knowing

A