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MS1 Spring > ICM 2 Psych Drugs > Flashcards

ICM 2 Psych Drugs Flashcards

1
Q

What is diphenhydramine used for?

A

To treat Dystonia (sustained muscle contraction) due to EPS

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2
Q

What SSRI should you NOT give to children because of the high suicide risk?

A

Paroxetine

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3
Q

Six SSRIs?

A

“Effective for sadness, panic, and compulsions”

Escitalopram, Fluoxetine & Fluvoxamine, Sertaline, Paroxetine, and Citalopram

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4
Q

Why are MAOIs rarely prescribed?

A

They can cause hypertensive crisis (tyramine is normally broken down by MAO & without it tyramine builds up - tyramine responsible for fight or flight response)

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5
Q

What dementia medication is glutamate-based?

A

Memantine

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6
Q

What medication is most effective in treating acute mania?

A

Valproate

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7
Q

Three SNRIs?

A

Venlafaxine

Desvenlafaxine

Duloxetine

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8
Q

What is Dantrolene used for?

A

To treat Neuroleptic Malignant Syndrome (lead pipe rigidity!!)

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9
Q

What are symptoms of severe Serotonin Syndrome?

A

diaphoresis, tachycardia, hyperthermia, hypertension, vomiting, diarrhea, muscle rigidity, fever, sweating, restlessness, agitation, delirium, tremor, hyperreflexia, clonus, bilateral Babinski sign

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10
Q

What antidepressant does not cause sexual dysfunction?

A

Buproprion

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11
Q

Six mood stabilizers?

A

CLLOT-V

Carbamazepine

Lamotrigine

Lithium

Oxcarbazepine

Topiramate

Valproate

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12
Q

What is the only FDA-approved drug for treating bulimia in adults?

A

Fluoxetine

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13
Q

What atypical antipsychotic has side effects of sedation and orthostatic hypertension?

A

Quetiapine

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14
Q

What are the three acetylcholinesterase inhibitor drugs used to treat dementia?

A

Donepezil, galantamine, rivastigmine

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15
Q

What atypical antipsychotic has a side effect of agrunulocytosis?

A

Clozapine

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16
Q

What is Eszopiclone used for?

A

Sleep aid

EsZZZopiclone

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17
Q

What antidepressant class causes QTc prolongation?

A

TCAs

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18
Q

What class of antidepressants are commonly prescribed for chronic pain and fibromyalgia?

A

SNRIs

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19
Q

Lithium side effects?

A

Leukocytosis, heart block, nephrotoxicity, hypothyroid, nephrogenic diabetes insipidus, weight gain, hand tremor

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20
Q

What is Zolpidem used for?

A

Sleep (its Ambien!)

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21
Q

Which TCA is used to treat GERD?

A

Doxapine

22
Q

What is Trazadone commonly used off-label for?

A

Sleep (side effect of priapism!)

TraZZZa-bone

23
Q

What TCA is used to treat neuropathy?

A

Amitriptyline

24
Q

Which two benzos are easiest on the liver and used to detox cirrhosis/hepatitis patients?

A

Lorazepam and Temazepam

25
Q

What is Temazepam used off-label for?

A

Sleep

26
Q

What will a patient with discontinuation syndrome present with?

A

headaches, dysphoric or irritable mood, flushing, dizziness, insomnia, tremor

27
Q

What antidepressant class is lethal in overdose?

A

TCAs

28
Q

What mood stabilizer has questionable efficacy in children?

A

Oxcarbazepine

29
Q

Three typical/first gen antipsychotics?

A

Chlorpromazine, fluphenazine, haloperidol

30
Q

What is Benzotropine used for?

A

To treat dystonia (sustained muscle contraction) due to EPS

31
Q

Two FDA-approved drugs for treating depression in children?

A

Escitalopram and Fluoxetine

32
Q

Which two benzos have an increased addiction risk?

A

Diazepam (valium) and Alprazolam (xanax)

33
Q

Which benzo is used for treating sleep walking, REM behavior disorder and narcolepsy?

A

Clonazepam

34
Q

Five TCAs?

A

D CAIN (think Danity Cain)

Doxapine, Clomipramine, Amitriptyline, Imipramine, Notriptyline

35
Q

Which SSRI has a high risk for discontinuation syndrome?

A

Paroxetine

36
Q

Three MAOIs?

A

SIP

Selegiline (B)

Isocarboxazid (A&B)

Phenelzine (A&B)

37
Q

What mood stabilizer has a high risk for Steven Johnson rash in Asian population?

A

Carbamazepine

38
Q

What is Buproprion commonly used for?

A

Depression (but not anxiety) and smoking cessation

Off-label for ADHD

39
Q

Mono amine oxidase B breaks down what neurotransmitters?

A

dopamine

40
Q

Mono amine oxidase A breaks down what neurotransmitters?

A

Serotonin and norepinephrine

41
Q

Side effects of Valproate?

A

Suicidal ideation, hepatitis/hepatotoxicity, neural tube defects, pregnancy class X, sedation, weight gain, bone marrow suppression, hirsutism, PCOS

42
Q

What atypical antipsychotic has a side effect of QT prolongation?

A

Ziprasidone

43
Q

What class of antipsychotics are stronger D2 blockers?

A

typical/first gen

44
Q

What mood stabilizer has a high risk for Steven Johnson rash?

A

Lamotrigine

45
Q

What else do atypical antipsychotics block?

A

5HT2A (serotonin) + 5HT2C & H1 histamine

46
Q

What TCA is used to treat enuresis?

A

Imipramine

47
Q

What is Buspirone used for?

A

FDA-approved for treatment of Generalized Anxiety Disorder (no panic disorder cross-over); onset of action is 3-4 weeks

48
Q

Five atypical/second gen antipyschotics?

A

Aripiprazole, Clozapine, Olanzapine, Quetiapine, Ziprasidone

49
Q

Who is Mirtazapine commonly prescribed to?

A

Depressed elderly who experience appetite reduction and insomnia

MirtaZZZapine

50
Q

What TCA is used to treat OCD?

A

Clomipramine

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