ICM 2 Psych Drugs

Question 1

What is diphenhydramine used for?

Answer 1

To treat Dystonia (sustained muscle contraction) due to EPS

Question 2

What SSRI should you NOT give to children because of the high suicide risk?

Answer 2

Paroxetine

Question 3

Six SSRIs?

Answer 3

“Effective for sadness, panic, and compulsions”

Escitalopram, Fluoxetine & Fluvoxamine, Sertaline, Paroxetine, and Citalopram

Question 4

Why are MAOIs rarely prescribed?

Answer 4

They can cause hypertensive crisis (tyramine is normally broken down by MAO & without it tyramine builds up - tyramine responsible for fight or flight response)

Question 5

What dementia medication is glutamate-based?

Answer 5

Memantine

Question 6

What medication is most effective in treating acute mania?

Answer 6

Valproate

Question 7

Three SNRIs?

Answer 7

Venlafaxine

Desvenlafaxine

Duloxetine

Question 8

What is Dantrolene used for?

Answer 8

To treat Neuroleptic Malignant Syndrome (lead pipe rigidity!!)

Question 9

What are symptoms of severe Serotonin Syndrome?

Answer 9

diaphoresis, tachycardia, hyperthermia, hypertension, vomiting, diarrhea, muscle rigidity, fever, sweating, restlessness, agitation, delirium, tremor, hyperreflexia, clonus, bilateral Babinski sign

Question 10

What antidepressant does not cause sexual dysfunction?

Answer 10

Buproprion

Question 11

Six mood stabilizers?

Answer 11

CLLOT-V

Carbamazepine

Lamotrigine

Lithium

Oxcarbazepine

Topiramate

Valproate

Question 12

What is the only FDA-approved drug for treating bulimia in adults?

Answer 12

Fluoxetine

Question 13

What atypical antipsychotic has side effects of sedation and orthostatic hypertension?

Answer 13

Quetiapine

Question 14

What are the three acetylcholinesterase inhibitor drugs used to treat dementia?

Answer 14

Donepezil, galantamine, rivastigmine

Question 15

What atypical antipsychotic has a side effect of agrunulocytosis?

Answer 15

Clozapine

Question 16

What is Eszopiclone used for?

Answer 16

Sleep aid

EsZZZopiclone

Question 17

What antidepressant class causes QTc prolongation?

Answer 17

TCAs

Question 18

What class of antidepressants are commonly prescribed for chronic pain and fibromyalgia?

Answer 18

SNRIs

Question 19

Lithium side effects?

Answer 19

Leukocytosis, heart block, nephrotoxicity, hypothyroid, nephrogenic diabetes insipidus, weight gain, hand tremor

Question 20

What is Zolpidem used for?

Answer 20

Sleep (its Ambien!)

Question 21

Which TCA is used to treat GERD?

Answer 21

Doxapine

Question 22

What is Trazadone commonly used off-label for?

Answer 22

Sleep (side effect of priapism!)

TraZZZa-bone

Question 23

What TCA is used to treat neuropathy?

Answer 23

Amitriptyline

Question 24

Which two benzos are easiest on the liver and used to detox cirrhosis/hepatitis patients?

Answer 24

Lorazepam and Temazepam

Question 25

What is Temazepam used off-label for?

Answer 25

Sleep

Question 26

What will a patient with discontinuation syndrome present with?

Answer 26

headaches, dysphoric or irritable mood, flushing, dizziness, insomnia, tremor

Question 27

What antidepressant class is lethal in overdose?

Answer 27

TCAs

Question 28

What mood stabilizer has questionable efficacy in children?

Answer 28

Oxcarbazepine

Question 29

Three typical/first gen antipsychotics?

Answer 29

Chlorpromazine, fluphenazine, haloperidol

Question 30

What is Benzotropine used for?

Answer 30

To treat dystonia (sustained muscle contraction) due to EPS

Question 31

Two FDA-approved drugs for treating depression in children?

Answer 31

Escitalopram and Fluoxetine

Question 32

Which two benzos have an increased addiction risk?

Answer 32

Diazepam (valium) and Alprazolam (xanax)

Question 33

Which benzo is used for treating sleep walking, REM behavior disorder and narcolepsy?

Answer 33

Clonazepam

Question 34

Five TCAs?

Answer 34

D CAIN (think Danity Cain) Doxapine, Clomipramine, Amitriptyline, Imipramine, Notriptyline

Question 35

Which SSRI has a high risk for discontinuation syndrome?

Answer 35

Paroxetine

Question 36

Three MAOIs?

Answer 36

SIP Selegiline (B) Isocarboxazid (A&B) Phenelzine (A&B)

Question 37

What mood stabilizer has a high risk for Steven Johnson rash in Asian population?

Answer 37

Carbamazepine

Question 38

What is Buproprion commonly used for?

Answer 38

Depression (but not anxiety) and smoking cessation Off-label for ADHD

Question 39

Mono amine oxidase B breaks down what neurotransmitters?

Answer 39

dopamine

Question 40

Mono amine oxidase A breaks down what neurotransmitters?

Answer 40

Serotonin and norepinephrine

Question 41

Side effects of Valproate?

Answer 41

Suicidal ideation, hepatitis/hepatotoxicity, neural tube defects, pregnancy class X, sedation, weight gain, bone marrow suppression, hirsutism, PCOS

Question 42

What atypical antipsychotic has a side effect of QT prolongation?

Answer 42

Ziprasidone

Question 43

What class of antipsychotics are stronger D2 blockers?

Answer 43

typical/first gen

Question 44

What mood stabilizer has a high risk for Steven Johnson rash?

Answer 44

Lamotrigine

Question 45

What else do atypical antipsychotics block?

Answer 45

5HT2A (serotonin) + 5HT2C & H1 histamine

Question 46

What TCA is used to treat enuresis?

Answer 46

Imipramine

Question 47

What is Buspirone used for?

Answer 47

FDA-approved for treatment of Generalized Anxiety Disorder (no panic disorder cross-over); onset of action is 3-4 weeks

Question 48

Five atypical/second gen antipyschotics?

Answer 48

Aripiprazole, Clozapine, Olanzapine, Quetiapine, Ziprasidone

Question 49

Who is Mirtazapine commonly prescribed to?

Answer 49

Depressed elderly who experience appetite reduction and insomnia MirtaZZZapine

Question 50

What TCA is used to treat OCD?

Answer 50

Clomipramine