IC1: Anatomy

Question 1

How does blood separate when collected with and without anticoagulant?

Answer 1

With: RBC, buffy coat, plasma
Without: Blood clots, serum (without fibrinogen)

Question 2

What are the protein components of plasma?

Answer 2

Albumin (osmotic pressure, lipid, steroid transport)
Globulins (ion, hormone, lipid transport)
Fibrinogen
Regulatory proteins (enzymes and hormones)

Question 3

What are the granulocytes? (3)

Answer 3

Neutrophils, basophils, eosinophils

Question 4

What are the agranulocytes? (2)

Answer 4

Lymphocytes, monocytes

Question 5

What is the most abundant type of WBCs?

Answer 5

Neutrophils

Question 6

Describe the lobes of a neutrophil’s nucleus

Answer 6

3-5 lobes

Question 7

What is the main function of neutrophils

Answer 7

Phagocytosis

Question 8

Describe the lobes of an eosinophil’s nucleus

Answer 8

2 lobes

Question 9

What are the main functions of eosinophils? (2)

Answer 9

Exocytosis of toxic substances on target cell’s surfaces
Phagocytosis

Question 10

Describe basophil’s nucleus

Answer 10

bilobed

Question 11

What are the two main components and respective functions of basophil granules?

Answer 11

Histamine (vasodilator, enhance capillary permeability)
Heparin (anticoagulant)

Question 12

Describe monocytes’ nucleus

Answer 12

Oval/kidney shaped, eccentrically palced

Question 13

What do monocytes mature to become after 24h in circulation?

Answer 13

Macrophages

Question 14

What are monocytes’ 3 main functions?

Answer 14

1. generates tissue macrophages
2. phagocytosing and digesting protozoa
3. antigen presentation

Question 15

Where can most of the body’s lymphocytes be found?

Answer 15

In connective tissue and lymphatic organs

Question 16

How long do platelets circulate for?

Answer 16

9-12 days