IBD: UC Flashcards
UC Definition
-chronic disease characterized by diffuse mucosal inflammation limited to the colon
UC Clinical Manifestations
- 5 to 30 stools per day with blood and mucus (severe)
- Cramping in LLQ abdomen relieved by BM
- Common nutritional deficits
- anemia, decreased albumin, weight loss
- fever (rare)
Severe UC
-bloody stool frequency of more than 5 per day with any one of the following:
- tachycardia (over 90 bpm)
- temp (over 37.8 C)
- anemia (less than 10.5 Hg)
- raised ESR (over 30)
Clinical Manifestations of Severe Complications
- arthritis 1 or more joints
- skin and mucous membrane lesions
- uveitis
- thromboemboli
- sclerosing cholangitis
- hemorrhage with anemia
- perforation
- rupture of bowel
- toxic megacolon
- carcinoma
Assessment for UC
- weight loss/pallor
- abdominal distension
- tenderness in the area of involvement
- abnormal bowel sounds
- presence of an inflammatory mass are common
- perianal abscess, fistula, skin tags, or anal stricture
UC Medical Therapy
-medication tx is based on the severity of symptoms
Five major classes used:
- aminosalicylates (5 ASA)
- glucocorticoid
- immunomodulators
- antibiotics
- biologic
UC Diagnosis
- rule out other infectious causes through stool cultures
- blood workup, check for anemia and infection
- prometheus panel
- small bowel follow through
- endoscopic exam: sigmoidoscopy, total colonoscopy
- chromoendoscopy
Goals for the Management of Acute Ulcerative Colitis
- induction of remission
- prevention of relapse
- tx of complications
UC Surgery
indications:
- fails to respond to tx
- exacerbations are frequent and debilitating
- massive bleeding, perforation, strictures and/or obstructions
- tissue changes suggest dysplasia is occurring
- cancer
25-40% of patients will need surgery
Steps to Surgery for UC
2 steps, 8 to 12 weeks apart
- Colectomy, rectal mucosectomy, ileal reservoir construction (temp. ileostomy)
- Closure of ileostomy to direct stool toward new reservoir 3-6 months
UC Surgery results
- decreased # BMs/day
- control of defecation at anal sphincter
Types of Ostomies
- Ileostomy
- Colostomy
Ileostomy description
opening into ileum to allow passage of intestinal content.
Intestine is sutured onto the skin surface creating a stoma
All portions of the large intestine are removed.
Can be permanent or temporary
Colostomy
opening into colon to allow passage of intestinal content
intestine is sutured onto the skin surface creating a stoma
Preoperative Care
- psych support and explanation
- enterostomal clinician for optimal placement of stoma
- diet modifications
- general preop teaching
- NG or intestinal tube post op
- antibiotics day before surgery
- laxatives, enemas evening before and morning of surgery
Preop diet modifications
- ↑ calorie
- ↑ protein
- ↑ carbs
- ↓ residue week before
- NPO after midnight
Ileostomy
- usually done for Crohn’s disease and ulcerative colitis
- permanent ostomy in RLQ abdomen
- Pouch must be worn at all times for liquid to semi-liquid drainage
- skin breakdown and fluid/electrolyte imbalance occur easily
Ileostomy Dietary Concerns
Goal: return to normal pre-surgical diet and avoid foods that cause diarrhea, gas, or obstruction
4-6 wks: low fiber diet
- prone to food blockage with non-digestible fiber intake (knows signs)
- use care when eating high fiber foods
Blockages
- Keep NPO
- Remove pouch if stoma swollen
- warm bath 15 minutes
- peri-stomal massage (knee chest position if possible)
- may use warm saline irrigation if other measures do not work
- do not irrigate routinely to regulate frequency of BM
- if blockage lasts for 2 hours or starts to vomit, call doctor, ostomy nurse or go to the ER
Colostomy Types
- Ascending colostomy
- transverse double barrel colostomy
- sigmoid colostomy
Ascending colostomy
- RUQ abdomen
- all portions distal are removed
- permanent colostomy
- feces is semiliquid
- skin breakdown common