IBD and Celiac Flashcards
What is the most common extra-intestinal symptom of IBD?
arthritis (large joints)
What can worsen symptoms in Crohn’s disease?
NSAIDs
Smoking
Which nutrient deficiencies are associated with Crohn’s
Fe
B12
What labs will be elevated in active moderate-severe IBD
ESR
CRP
What is 1st line treatment for UC
Salicylates-5 ASA
What is the definitive surgical cure for UC?
proctocolectomy
What must be taken with Sulfasalazine?
folic acid
What is important to remember about the corticosteroids
slow taper!
What are the 1st line antibiotics used in Crohn’s disease?
Flagyl and Cipro
Risks of Mercaptopurine or Imuran (azathioprine)
- bone marrow suppression
- Lymphoma
- pancreatitis
- hepatotoxicity
Consequences of exposure to gluten in Celiac
- crypt hyperplasia
- villous atrophy in small intestine**
Celiac: clinical presentation
- diarrhea
- bulky, foul-smelling stool
- floating stool
- bloating
- flatulence
Celiac complications/other symptoms
MALABSORPTION
- Fe deficiency anemia
- Osteopenia
- Dematitis herpetiformis (really itchy!)
- Vitamin B deficiencies