IAN EGG LECS Flashcards
1
Q
What’s the aim of SAR?
A
To identify pharmacophore of a drug
2
Q
Electronic properties are described by what
A
Hammett substituent constant (Olaf)
3
Q
What’s molar refractivity
A
Quantifies the volume occupied by an atom or group of atoms
4
Q
What’s the 5 stages of drug discovery
A
- Choose target
- Biology validation
- Lead discovery
- SAR/refinement
- Lead optimisation
