I. Osteology: Cells, matrix, ossification, bone density, bone variation Flashcards
What are the four basic tissues of the human body?
epithelial, muscle, neural and connective
What is osteology?
the study of bone
What are the three primary cell types of bones?
osteoblasts, osteocytes, and osteoclasts
What is the fuction of each type of bone cell?
Osteoblast-form bone
Osteocyte- maintain and nurture bone
Osteoclast0 remodel bone
What are the bone cells embedded in?
an amorphous matrix consisting of groudn substance, protein fibers and various minerals
What is the primary constituent of the ground substance?
glycosaminoglycans
What types of glycosaminoglycans predominate in bone?
chondroitin sulfate, keratin sulfate and hyularonic acid
What is the principal type of protein fiber in bone?
Collagen type 1
What are the primary constituents of the bone mineral?
calcium, phosphate, citrate and carbonate ions
What is the most frequently described deposit in bone?
hydroxyapatite
Bone is also the repository for what additional ions?
sodium, magnesium, flouride, lead, strontium and radium
What is wolff’s law as it pertains to bone?
living tissue will respond to stressors; bone is formed or absorbed in response to various stressors
***What 3 responses of “living” bone were stressed in class?
it has the ability to heal, to remodel under stressors and to age
Bone is the embryological derivative of which specific connective tissue?
mesenchyme and/or cartilage
What is the name given to the pattern of ossification in mesenchyme?
intramembranous ossification