I- https://www.livescience.com/46147-animal-data-unreliable-for-humans.html

Question 1

I1- inaccuracy

Answer 1

• A 2008 study in the journal Alternatives to Laboratory Animals showed that more than 80 HIV/AIDS vaccines successful in nonhuman primates failed in human trials.

Question 2

I2- accuracy

Answer 2

• According to a 2004 study in the journal Stroke, more than 4,000 studies report efficacy of more than 700 treatments of stroke in animal models. Yet none of the approximately 150 of these treatments tested in humans showed clinical benefit, as reported in a 2005 paper in the International Journal of Neuroprotection and Neuroregeneration.

Question 3

I3- inaccuracy

Answer 3

• Drugs intended to reduce inflammation in critically ill patients, previously tested in mice, failed in nearly 150 human critical trials according to a 2013 study in Proceedings of the National Academy of Sciences.

Question 4

I4- accuracy

Answer 4

• A 2004 study from the U.S. Food and Drug Administration found that 92 percent of drugs entering clinical trials following animal testing fail to be approved.
• Of those approved, half are withdrawn or relabeled due to severe or lethal adverse effects not detected during animal tests.