I: Foundational Knowledge Flashcards
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planes of section (3)
frontal:coronal, sagittal:median, horizontal:axial
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directional nomenclature (5)
cranial:caudal, ventral:dorsal, medial:lateral, proximal:distal, flexion:extension
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major body cavities (2)*
dorsal, ventral (includes subcavities: thoracic and abdominal)
*separated by diaphragm
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tissue types (4)
epithelial, connective, muscular, nervous
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relationship between input and output of neurons
dendrites:input :: axons:output
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relationship between myelination in the CNS and PNS
oligodendrocytes myelinate axons in the CNS :: Schwann cells myelinate axons in the PNS
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action potentials (APs) (6)
specialized by axons, originate at the trigger zone, insulated by myelin sheath, all-or-nothing (threshold is reached or is not reached), terminate at boutons, resting potential restored by Na+/K+ pump
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major divisions of the PNS (2)*
somatic: action and awareness :: autonomic/visceral:detects and acts on body’s internal environment
* autonomic/visceral subdivided into parasympathetic (homeostasis) and sympathetic (fight or flight)
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cranial nerves V and VII through XII
V:trigeminal, VII:facial, VIII:vestibulocochlear, IX:glossopharyngeal, X:vagus, XI:spinal accessory, XII:hypoglossal
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trigeminal nerve (5)*
CN V, three major branches (ophthalmic, maxillary, mandibular), face sensation, muscles of mastication and tensor tympani
*oral stage of swallowing
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facial nerve (4)*
CN VII, taste anterior 2/3 tongue, facial expression, salivation
*oral stage of swallowing AND speech articulation
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glossopharyngeal nerve (5)*
CN IX, taste posterior 1/3 tongue, sensation of middle ear and upper pharynx, motor innervation of stylopharyngeus, gag reflex
*oral and pharyngeal stages of swallowing
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vagus nerve (7)
CN X, sensation of lower pharynx, motor innervation of pharyngeal-laryngeal muscles of soft palate, velum elevation, gag reflex, VF tension, add-abduction
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spinal accessory nerve (2)
CN XI, motor innervation of sternocleidomastoid and trapezius muscles (for head turning and shoulder elevation)
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hypoglossal nerve (3)
CN XII, motor innervation of intrinsic tongue muscles, oral stage of swallowing (bolus formation and propulsion)
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CNS meninges layers (3)
meninges cover CNS in three protective layers (pia, arachnoid, dura matter** – think PAD)
**listed from deep to superficial
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CSF (3)
cerebrospinal fluid, flows between pia and arachnoid layers of meninges, brain floats in CSF for protection from mechanical injury
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dura mater (2)
encapsulates brain and spinal cord, physically separates major regions of the brain
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in reference to separation between the brainstem and the spinal cord, ‘There is continuity in much of the neuroanatomy, but one identifying feature is that…’
‘…the corticospinal fibers in the pyramidal tracts cross the midline (decussate) in the medulla and the travel in the lateral corticospinal tracts within the spinal cord.’
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brainstem (3)
region of the brain spanning between forebrain and spinal cord, the route through which nearly all neural information travels between the body and the brain, three segments (medulla oblongata, pons, midbrain)
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medulla oblongata of the brainstem and CN involvement (2)
X:larynx, pharynx and upper esophagus, XII:tongue
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pons of the brainstem and CN involvement (2)
V:mastication and sensory nuclei for the head, VII:facial expressions
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cerebellum (2)
important role in motor control, lesions do not cause paralysis but may cause ataxia
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reticular formation (3)
centered primarily in the pons, coordinate muscle functions of the body and head, guide attention and arousal
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CNS lobe anatomy (4)*
frontal, parietal, temporal, occipital
*marked by/at central sulcus
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frontal lobe (5)
anterior to central sulcus and superior to lateral fissure
executive function (prefrontal cortex), language production (L inferior frontal gyrus of the prefrontal cortex), skilled movements (premotor cortex), motor strip which sources majority of body motor control signals (precentral gyrus – site of primary motor cortex)
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parietal lobe (2)
posterior to central sulcus and superior to lateral fissure
body sensation including hearing and vision
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temporal lobe (3)
inferior to lateral sulcus and anterior to occipital lobe
primary auditory cortex (Heschl’s gyrus), language comprehension (Wernicke’s area)
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occipital lobe (2)
most posterior lobe of the brain (no distinct separation from neighboring lobes)
higher-order processing of visual information (primary visual cortex)
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limbic cortex (4)
memory, emotion, drive-related behavior, primitive behavior
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basal ganglia (4)
aka basal nuclei, guide behavior via inhibition, four subdivisions (striatum, globes pallidus, substantia nigra, subthalamic nucleus, dopamine production
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diencephalon (1)*
four regions (epithalamus, thalamus, subthalamus, hypothalamus)
*thalamus relays majority of sensory information, motor pathways of basal ganglia and cerebellum travel through thalamus en route to motor cortex – the gatekeeper!
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pyramidal system (4)
aka direct motor pathway, responsible for skilled-voluntary movements of extremities, two major pathways (corticospinal tract, corticobulbar tract), houses axons which descend from UMNs in the cerebrum to LMNs in the spinal cord and brainstem
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corticospinal tract of the pyramidal system (3)
houses descending fibers that decussate from lateral corticospinal tract, main function is contralateral-fine-rapid limb control
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corticobulbar tract of the pyramidal system (2)
UMNs in the cerebrum descend to LMNs in the brainstem, main function is to control muscles of the face-head-neck
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extrapyramidal system (5)
aka indirect motor pathways, involved in reflexes and coordination of muscle groups, involved in regulation of posture-balance-tone, three tracts (rubrospinal, reticulospinal, vestibulospinal), two control circuits (cerebellar, basal ganglia)
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basal ganglia of the extrapyramidal system (3)*
indirectly regulates motor activity, refines movement by increasing precision and form, two predominant pathways (direct:output, indirect:input)
*interruptions to these pathways leads to movement disorders of initiation or muscle tone!
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ascending pathways (1)*
contain sensory signals called afferent signals (Afferent:Arrive) because information propagates from the body’s periphery to the brain
*remember, descending nerve impulses aka efferents exit the brain (Efferent:Exit)
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veins vs arteries
veins:carry deoxygenated blood and waste from body back to heart and lungs :: arteries:deliver oxygen and nutrient-rich blood to the body
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carotid arteries (1)*
two carotid artery branches (internal*, external)
*internal carotid arteries subdivided into anterior cerebral arteries and middle cerebral arteries and supply blood to the brain
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middle cerebral arteries of the internal carotid arteries (1)
supply blood to the brain (lateral frontal lobes, lateral temporal lobes, portions of parietal lobe, basal ganglia)
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subclavian arteries (1)
supply blood to spinal cord, brainstem, cerebellum, occipital lobe, thalamus
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respiratory anatomy (4)*
L lung:two lobes :: R lung:three lobes, trachea (average 10-16 cm long), major muscles of respiration (diaphragm, abdominals, external intercostals, internal intercostals), accessory muscles (sternocleidomastoid, scalene)
*aspiration is more common in the R lung!
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inspiration during quiet breathing (3 steps)*
contraction lowers-flattens diaphragm -> lungs expand and create negative pressure -> negative pressure draws air inward (inhalation)
*during quiet breathing, inspiration:40% :: exhalation:60%, changes to I:10% :: E:90% during speech breathing
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respiratory volumes/capacities (4)
four discreet and non-overlapping volumes aka capacities (tidal, inspiratory reserve, expiratory reserve, residual)
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tidal vs residual volume
TV:average volume air exchanged per cycle of passive breathing :: RV:volume air remaining in lungs after maximum exhalation
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inspiratory reserve vs expiratory reserve volume
IRV:max volume air that can be inspired above the level of tidal inspiration :: ERV:max volume air that can be expired below relaxation volume
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respiratory capacities/combined volumes (4)*
vital capacity (IRV+TV+ERV), functional residual capacity (ERV+RV), inspiratory capacity (TV+IRV), total lung capacity (IRV+TV+ERV+RV)
*VC is approximately 4 L:women and 5 L:men
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larynx (5)
organ important for airway protection and phonation, located C3-C6, connects oropharynx and laryngopharynx to trachea, single-midline cartilages (thyroid, cricoid, epiglottis), paired carriages (arytenoids, corniculates, cuneiforms)
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functions of intrinsic muscles of the larynx (3 groups)*
pitch (vocalis, cricothyroid, thyroarytenoid), adduction (transverse interarytenoids, oblique arytenoids, lateral cricothyroids), abduction (posterior crivoarytenoids)
*innervated by CN X
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extrinsic suprahyoid muscles of the larynx
hyoid elevation (mylohyoid, geniohyoid, stylohyoid, diagastric muscle)
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extrinsic infrahyoid muscles of the larynx
hyoid/thyroid depression (sternohyoid, omohyoid, thyrohyoid, sternothyroid)
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layers of the vocal folds (5)*
body (thyroarytenoid, deep lamina propria, intermediate lamina propria) and cover (superficial lamina propria and epithelium)
*body is stiffer than cover
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myoelastic aerodynamic theory (5 steps)
VFs adduct and close the glottis -> subglottic pressure builds and blows open VFs (this is where you see mucosal wave via sheathing motion) -> Bernoulli effect -> decrease in air pressure and pliability of VFs closes VFs -> subglottic pressure builds for next cycle
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muscles of mastication (4)*
all muscles of mastication are paired and are innervated by trigeminal CN V (masseters, temporals, medial pterygoids, lateral pterygoids)
*temporomandibular joint aka TMJ allows three planes of direction
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muscles of the tongue (8)*
intrinsic (superior longitudinal, inferior longitudinal, transverse, vertical), extrinsic (genioglossus, hyoglossus, styloglossus, palatoglossus)
*almost all innervated by hypoglossal CN XII
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three major systems of speech production (3)
respiratory:driving force of voice production and articulation :: laryngeal:valving for airway protection and VF vibration :: supralaryngeal:filter and shape phonation via resonances
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frequency (2)*
(f) is a count of the number of repetitions of a cyclic pattern in 1 second, measured in Hertz (Hz) or kilohertz (kHz)
* (f) is perceived as pitch, equal changes in (f) DO NOT correspond to equal changes in pitch
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semitones vs octaves*
semitones: intervals between sounds (1 semitone change is always perceptually equal), octaves:doubling of (f)
* 12 semitones=1 octave
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period (2)
(T) is the duration of one cycle, (f) and (T) have an inverse relationship*
*T=1/f and f=1/T – if (f)=100 Hz then (T)=0.01 seconds
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amplitude (4)
(A) is the physical measure of extent of vibrational change from resting position, measured in decibels, two measurements (peak amplitude:max pressure reached by pressure wave, root mean square amplitude:average amplitude of a sound over some period of time), perceived as loudness