i and d mcqs Flashcards
the lymphoid tissue most closely associated with immune responses to gut pathogens is the:
A- MALT
B lymph nodes
C secondary lymph nodes
D mucosal tissue
E M cells
MALT
the cell type most closely associated with chronic inflammation is the
A basophil
B b cell
C Mast cell
D Nk cell
E macrophage
macrophage
the area of the lymph node closely associated with class switching of antibodies
A medullary sinus
B primary follicle
C secondary follicle
D germinal centre
E paracortex
D germinal centre
the most important target site for penicillin is the
A plasma membrane
B cell wall
C DNA gyrase
D ribosome
E dihydrofolate reductase
B cell wall
one of the following is only found in the uk as an imported fungal infection
A cryptococcosis
B histoplasmosis
Cinvasive candidiasis
D invasive aspergillosis
E pneumocystis infection
b histoplasmosis
the pathogenesis of severe malaria is a consequence of
A reduced circulating levels of inflammatory mediators
B macrophage activation
C over production of tumour necrosis factor il1 il2 and interferon gamma
D toxins produced during infection
E activation of hosts immune system
over production of tumour necrosis factor il1 il2 and interferon gamma
following a routine non complicated surgical procedure scar formation is a result of
A basement membrane disruption as part of surgery
B early mobility
C infection
D healing by secondary infection
E wound dehisence
a basement membrane disruption
the most rapid means of spread of infection in a population is
A sexual transmission
B faecal oral route
C congenital from mother to foetus
D insect bite
E respiratory route via infectious aerosols
E respiratory route via infectious aerosols
negative staining using india ink is used with a light microscope to visualise
A spirochaetes
B capsules
C endospores
D flagella
E pili fimbriae
b capsules
aspergillus species are important in medicine because they
A can invade lung and blood vessels in immunocompromised people
B are ubiquitous environmental fungi
C are thermophiles that can survive being at 55
D produce asexual spores known as conidia
E grow as filaments in a mycelium
A can invade lung and blood vessels in immunocompromised people
the most important characteristic of entamoeba histolytica is that it
A produces cysts which survive in the environment
B can cause mild or asymptomatic diarrhoea
C can cause severe dysentery
D may be acquired via anal sexual activity
E is common in tropical and subtropical countries
c entamoeba histolytica can cause severe dysentery
urinary tract infections have an important impact in the community because they
A can cause recurrent infections in 20-30% women
B rarely caused by anaerobes
C associated with minor anatomical abnormalities of the urinary tract and kidneys of baby boys
D most frequently caused by e coli
E arise because urine is an excellent growth medium
can cause recurrent infections in 20-30% women
capnophiles are bacteria that
A commonly occur in human commensal microflora
B are able to grow in an environment with 2-10% oxygen
C grow in an environment that contains 78% nitrogen
D are aerobic organisms
E require 5-10% of carbon dioxide
E
which one of the following statements is correct
A vertical transmission of viruses between siblings is common in the uk
B most human viruses are readily transmitted to farm animals but the converse is not true
C faeco oral transmission of hepatitis C virus typically occurs in intravenous drug abusers
D transmission can always be prevented by strict personal hygiene
E blood borne viruses may be transmitted noscomially
E
which one of the following statements is correct
A) herpesvirus divides within host cell membranes
B) uncoating is the term used to describe the release of the viral genome from the nucleocapsid
C) negative sense rna acts as viral mrna
D) viral early genes are transcribed after replication of the genome encode structural proteins
E virus replication inevtiably leads to host cell lysis
B
