HYS CH7.1 The Genetic Code Flashcards
central dogma
translation
mRNA –> proteins
genetic code rules
takes 3 amino acids to specify an amino acid
anticodons
on tRNA
each codon is recognized by complementary anticodon in ribosome
how many codons?
which codon position shows degeneracy?
what does it mean to unabiguous?
64 codons specifies 20 amino acids
third one shows degeneracy
unabiguous means each 3 letter codon specifies only one amino acid
wobble base pairs
first two bases are significant in identifying amino acid
last base - wobble pase - tRNA literally wobbles
if wrong TRNA brought in at pos its likely silent mutation – no effect on protein
point mutation
affects 1 nucleotides
silent mutation
point mutation that does not affect overall protein
missense mutation
one amino acid is substituted for another due
expressed mutation –> effects primary sequence
nonsense mutation
change codon from amino acid to stop codon bc they prematurely truncate or end an amino acid
start codon
AUG start mRNA for protein
codes for methionine
every pre processed codon begins with methionine
AUG like August – school starts
stop codon
UAA
UGA
UAG
translation terminates
UAA - U are annoying
UGA - U go away
UAG - U are gone