Hypothyroidism Flashcards
Main symptoms
Cold
Weight gain
Constipation
Bradycardia
Symptoms - other
Lethargy
Muscle cramps
Slow movement
Slow thoughts
Depression
Hair thinning
Tests
High TSH
Low T4 (thyroxine)
Low T3 (triiodothyronine)
Levothyroxine/Liothyronine
Synthetic thyroid hormones as replacement therapy
Levothyroxine
Drug choice
Dose - question doses above 200 mg
How to take - in the morning at least 30 mins before breakfast, caffeine.
Liothyronine
More rapid effect & potent
Use - ideal in severe hypothyroid emergencies.
Switching brand - not bioequivalent
Initial dose
If too high - metabolism increases rapidly and causes hyperthyroidism symptoms
Reduce dose or WITHOLD for 1-2 days and restart at lower dose