Hyperthyroidism Flashcards
1
Q
Main symptoms
A
Heat intolerance
Weight loss
Diarrhoea
Tachycardia
2
Q
Other symptoms
A
Excitability
Tremors
Angina pain
Sweating
Arrhythmias
3
Q
Tests
A
Low TSH
High T4 (thyroxine)
High T3 (Triiodothyronine)
4
Q
Treatment
A
Carbimazole
Propylthiouracil
5
Q
MoA
A
Anti-thyroid drugs interfere with synthesis of thyroid hormones
6
Q
Carbimazole
A
Drug of choice
SE:
Bone marrow suppression
Rashes/itching
7
Q
Bone marrow suppression
A
Agranulocytosis + Neutropenia
Pt counselling = report signs of infection e.g. fever, malaise, mouth ulcers, sore throat
8
Q
Propylthiouracil
A
Alternative
SE = hepatotoxicity
9
Q
Hyperthyroidism - pregnancy
A
Blocking replacement regimen and radioactive iodine is C/I
10
Q
1st trimester
A
Propylthiouracil
11
Q
2nd trimester
A
Carbimazole
