Hypothyroidism Flashcards

1
Q

What is hypothyroidism?

A

Inadequate output of the thyroid gland

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2
Q

What is the commonest cause of hypothyroidism?

A

Hashimoto’s thyroiditis

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3
Q

What auto-antibodies are associated with Hashimoto’s thyroidits?

A

Anti-TPO
Antithryoglobulin antibodies

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4
Q

What medications can cause hypothyroidism?

A

Lithium
Amiodarone

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5
Q

What is the cause of secondary hypothyroidism?

A

Hypopituitarism caused by infection, tumours, Sheehan’s syndrome (vascular), radiation

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6
Q

Features of hypothyroidism?

A

Weight gain (10% weight loss)
Fatigue
Dry skin
Coarse hair
Alopecia
Fluid retention
Heavy/irregular periods
Constipation

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7
Q

Management of hypothyroidism?

A

Levothyroxine

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8
Q

What is levothyroxine?

A

Synthetic T4

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9
Q

What are thyroid hormones like in primary hypothyroidism?

A

Low T4 and T3
High TSH

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10
Q

What are thyroid hormones like in secondary hypothyroidism?

A

Low T3 and T4
Low TSH

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