Hypothalamic Pituitary

Question 1

Which drug is used for milk letdown and induction of labor?

Answer 1

Oxytocin

Question 2

Drug selective for V2 receptor and is synthetic vasopressin analog and treats nephrogenic Diabetes Insipidus.

Answer 2

Desmopressin

Question 3

Blocks IGF-1 secretion and acts as GH antagonist. Used when octerotide and other somatostatin doesn’t work

Answer 3

Pegvisomat

Question 4

MoA of Somatotropin

Answer 4

Stimulate cartilage and bone growth. Increase protein disposition and fat utilization and reduce carb utilization.

Question 5

Drug used to treat GH deficiency and promotes linear growth.

Answer 5

Somatotropin

Question 6

MoA of Vasopressin

Answer 6

V1 receptor–>IP3/DAG and V2–>cAMP. renal effect

Question 7

Drug used for Syndrome of Inappropriate Secretion of ADH (SIADH)

Answer 7

Conivaptan

Question 8

Somatostatin analog used to treat GH overactivity and acromegaly.

Answer 8

Octerotide

Question 9

Drug used to treat hyperprolactemia and is DA analog

Answer 9

Bromocriptine

Question 10

Drug for Larson Syndrome and lack of GH response or IGF-1

Answer 10

Mecasermin

Question 11

Non-peptide vasopressin antagonist. High affinity for V2

Answer 11

Conivaptan