Hyposecretion of adenohypophysis

Question 1

5 classes of anterior pituitary hormones

Answer 1

1) FSH/LH
2) GH
3) TSH
4) ACTH
5) PROLACTIN

Question 2

Explain primary, secondary, tertiary endocrine gland disease

Answer 2

1- issue with gland itself
2-issue with adenohypophysis
3-issue with hypothalamus

Question 3

What is panhypopituitiarism

Answer 3

Decreased production of all anterior pituitary hormones

Question 4

Causes of panhypo

Answer 4

ACQUIRED:
Radiation
Infection
Traumatic brain injury
Infiltrative disease
Pituitary apoplexy
Tumour
Inflammatory 
Peri-partum infarction

more rare- congenital

Question 5

What causes congenital panhypopituitarism

Deficient in?

Appearance in MRI

Appearance of individuals

3 types of panhypopituitarism

Answer 5

Usually due to mutations of TF genes for Adenhypophyis

GH and at least 1 more anterior pituitary hormone

Short stature

1) Simmond’s disease
2) Sheehan’s
3) Pituitary apoplexy

Question 6

Simmond’s disease symptom due to?

Answer 6

Deficient FSH/LH, ACTH, TSH

Question 7

Symptoms

Answer 7

FSH/LH
-Secondary hypogonadism
-Reduced libido
-Secondary amenorrhoea
-Erectile dysfunction
ACTH
-Secondary hypoadrenalism (cortisol deficiency)
-Fatigue
TSH
-Secondary hypothyroidism
-Fatigue

Question 8

Sheehan’s syndrome difference with

Answer 8

Only in women