Hyponatraemia Flashcards

1
Q

symptoms of hyponatraemia

A

increased skin turgor
tachycardia
hypotension
red cracked tongue
confusion
seizures

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2
Q

what % of our bodies are water

A

60% men
55% women

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3
Q

what are the three compartments of fluid in the body and how much is found in each

A

intracellular - 30L
interstitial - 9L
vascular - 3L

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4
Q

where is sodium principally found

A

extracellular compartments - interstitial and vascular spaces

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5
Q

what forces are involved in water movement out of the cell

A

internal hydrostatic pressure - pushes
external osmotic pressure - pulls

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6
Q

what forces are involved in water movement into the cell

A

external hydrostatic pressure - pushes
internal osmotic pressure - pulls

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7
Q

is water movement passive or active

A

passive (follows Na+)

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8
Q

is Na+ movement passive or active

A

active

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9
Q

how does our body respond to an alteration in tonicity

A

it moves water to dilute the high tonicity

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10
Q

volume deplete is aka

A

hypovolaemic

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11
Q

volume overloaded is aka

A

hypervolaemic

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12
Q

what are the three forms of hyponatraemia

A

normovolaemic
hypovolaemic
hypervolaemic

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13
Q

disease states which cause fluid loss

A

haemorrhage
vomiting
diarhhoeas
burns
diuretic states (e.g. hypercalcaeimia, diabetes mellitus)
sequestration

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14
Q

what is sequestration and give an example

A

when one of the interstitial spaces becomes inflamed and collects up to 4L of fluid
this dehydrates the rest of the body
e.g. pneumonia

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15
Q

iatrogenic causes of fluid loss

A

diuretics
stomas/fistulae
gastric aspiration

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16
Q

disease states which cause fluid gain

A

heart failure
liver failure
renal failure
hypothyroidism
psychogenic polydipsia
ADH excess

17
Q

iatrogenic causes of fluid gain

A

IV fluids
supplemental nutrition

18
Q

what changes in Na+ and water can lead to hyponatraemia

A

water gain
water gain > Na+ gain
Na+ loss > water loss
Na+ loss and water gain

19
Q

what would be the volume state of someone who is hyponatraemic due to water gain

A

normovolaemic or mildly hypervolaemic

20
Q

what would be the volume state of someone who is hyponatraemic due to Na+ and water gain

A

hypervolaemia and interstitial oedema

21
Q

what would be the volume state of someone who is hyponatraemic due to Na and water loss

A

hypovolaemia

22
Q

causes of normovolaemic/hypervolaemic hyponatraemia

A

SIADH
hypothyroidism
iatrogenic

23
Q

causes of hypervolaemic hyponatraemia

A

heart failure
liver failure
nephrotic syndrome

24
Q

treatment of hypervolaemic hyponatraemia

A

rapid salt rich fluid administration