Hypomagnesaemia Flashcards

1
Q

name the causes of low magnesium

A
  • drugs
  • total parenteral nutrition
  • diarrhoea
  • alcohol
  • hypokalaemia
  • hypercalaemia
  • metabolic disorders
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2
Q

what drugs can lead to hypomagnesaemia?

A
  • diuretics
  • proton pump inhibitors
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3
Q

how does hypercalcaemia lead to hypomagnesaemia?

A

calcium and magnesium functionally compete for transport in the thick ascending limb of the loop of henle

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4
Q

what metabolic disorders can lead to hypomagnesaemia?

A
  • gitleman’s
  • bartter’s
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5
Q

what features of hypomagnesaemia may be similar to hypocalcaemia?

A
  • paraesthesia
  • tetany
  • seizures
  • arrhythmias
  • decreased PTH scretion –> hypocalcaemia
  • ECG features
  • exacerbates digoxin toxicity
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6
Q

what is the management of hypomagnesaemia <0.4mmol/L or tetany, seizures or arrhythmias?

A

IV magnesium (e.g. 40 mmol of magnesium sulphase over 24 hours)

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7
Q

what is the management of hypomagnesaemia >0.4mmol/L?

A

oral magesium salts (10-20 mmol orally per day in divided dosese)

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8
Q

what is a side-effect of oral magnesium salts?

A

diarrhoea

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