Hyperthyroidism

Question 1

Result of excessive

thyroid function

Answer 1

Hyperthyroidism

Question 2

Defined as the state of thyroid hormone excess

Answer 2

Thyrotoxicosis

Question 3

Major etiologies of thyrotoxicosis are

Answer 3

Graves disease
TMNG
Toxic adenomas

Question 4

True of Grave’s disease

a. accounts for only 20% of thyrotoxicosis
b. Occurs in 2% of women
c. Typically occurs in the elderly
d. Frequently begins before adolescence

Answer 4

B

a. accounts for 60-80%of thyrotoxicosis
b. Occurs in 2% of women
c. Occurs between 20 and
50 years of age
d. Rarely begins before adolescence

Question 5

The hyperthyroidism of Graves’ disease is caused by

Answer 5

Thyroid stimulating immunoglobulin (TSI)

Question 6

TSI can be detected by bioassays or by using the more widely available

Answer 6

Thyrotropin-binding inhibitory immunoglobulin (TBII) assays.

Question 7

Which of the following is false:

a. Smoking is a major risk factor for ophthalmopathy
b. Sudden increase in iodine intake make precipitate graves
c. There is a 3 fold increase in occurrence of Graves in the peripartum period
d. Graves may occur after HAART

Answer 7

c. There is a 3 fold increase in occurrence of Graves in the POSTpartum period

Question 8

Play a major role in thyroid-associated ophthalmopathy

Answer 8

Cytokines

Question 9

In certain patients, features of thyrotoxicosis may be subtle or masked, and
patients may present mainly with fatigue and weight loss, a condition
known as?

Answer 9

Apathetic thyrotoxicosis.

Question 10

Which of the following is TRUE regarding Thyrotoxicosis:
a. Weight gain does not occur in patients
b. Prominent features include hyperactivity, nervousness, and
irritability
c. A common manifestation is proximal myopathy with fasciculation
D. Thyrotoxicosis is sometimes associated with a form of hypokalemic periodic
paralysis; this disorder is particularly common in Asian females

Answer 10

Which of the following is TRUE regarding Thyrotoxicosis:

B

a. Weight gain can occur in 5 % of patients
b. Prominent features include hyperactivity, nervousness, and
irritability
c. A common manifestation is proximal myopathy withOUT fasciculation
D. Thyrotoxicosis is sometimes associated with a form of hypokalemic periodic
paralysis; this disorder is particularly common in Asian males