Hyperthyroid Flashcards
What are the types of hyperthyroid?
Subclinical
Primary
Secondary
Thyrotoxicosis
What causes primary hyperthyroid?
Autoimmune
Toxic multi nodular goitre
Toxic adenoma
What is the most common cause of hyperthyroid?
Grave’s
What is the most common cause of hyperthyroid in the elderly?
Toxic multi nodular goitre
What antibodies are present in Grave’s disease?
TSH receptor antibodies
What is a secondary cause of hyperthyroid?
TSH secreting pituitary adenoma
What are some causes of thyrotoxicosis?
condition of high thyroid hormones, irrespective of cause
Destructve thyroiditis- postpartum, amiodarone induced
Excessive thyroxine administration
What is the presentation of hyperthyroid?
Weight loss Heat intolerance, sweaty palms Anxiety, irritability Palpitations Hyperreflexia, tremors Light periods Bowel frequency Goitre Thyroi eye disease
What investigations are done for hyperthyroid?
TFTs
Autoantibodies
FBC, U&Es
What are the management options for hyperthyroid?
Radioactive iodine
Antithyroid drugs
Surgery
What is the radioactive iodine management of hyperthyroid?
High dose ablative therapy- very common
What is the risk with high dose ablative therapy?
Hypothyroid
What is an antithyroid drug?
Carbimazole
What are the side effects of carbimazole?
Rash
Agranulocytosis
When is subclinical hyperthyroid treated?
Considered if persistent, symptomatic, in elderly or those with high cardiac risk