Hyperthyroid Flashcards

1
Q

What are the types of hyperthyroid?

A

Subclinical
Primary
Secondary
Thyrotoxicosis

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2
Q

What causes primary hyperthyroid?

A

Autoimmune
Toxic multi nodular goitre
Toxic adenoma

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3
Q

What is the most common cause of hyperthyroid?

A

Grave’s

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4
Q

What is the most common cause of hyperthyroid in the elderly?

A

Toxic multi nodular goitre

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5
Q

What antibodies are present in Grave’s disease?

A

TSH receptor antibodies

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6
Q

What is a secondary cause of hyperthyroid?

A

TSH secreting pituitary adenoma

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7
Q

What are some causes of thyrotoxicosis?

condition of high thyroid hormones, irrespective of cause

A

Destructve thyroiditis- postpartum, amiodarone induced

Excessive thyroxine administration

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8
Q

What is the presentation of hyperthyroid?

A
Weight loss
Heat intolerance, sweaty palms
Anxiety, irritability
Palpitations
Hyperreflexia, tremors
Light periods
Bowel frequency
Goitre
Thyroi eye disease
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9
Q

What investigations are done for hyperthyroid?

A

TFTs
Autoantibodies
FBC, U&Es

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10
Q

What are the management options for hyperthyroid?

A

Radioactive iodine
Antithyroid drugs
Surgery

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11
Q

What is the radioactive iodine management of hyperthyroid?

A

High dose ablative therapy- very common

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12
Q

What is the risk with high dose ablative therapy?

A

Hypothyroid

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13
Q

What is an antithyroid drug?

A

Carbimazole

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14
Q

What are the side effects of carbimazole?

A

Rash

Agranulocytosis

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15
Q

When is subclinical hyperthyroid treated?

A

Considered if persistent, symptomatic, in elderly or those with high cardiac risk

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16
Q

What are the complications of hyperthyroid?

A

Thyroid storm
Decreased bone density
AF

17
Q

What is the presentation of a thyroid storm?

A
Fever >40
AF
Hypertension, progressing to hypotension and shock
D&V
Agitation
18
Q

What is the management of a thyroid storm?

A

Iodine and antithyroid drugs
Fluids and temperature regulation
Beta blockers

19
Q

What are the risks of hyperthyroid management?

A

Hypothyroid

Antithyroid drugs- agranulocytosis